exo-7-(tert-butoxycarbonyl)-7-aza-bicyclo[2.2.1]heptane-2-carboxylic acid methyl ester racemate

Base Information

Chemical Name:exo-7-(tert-butoxycarbonyl)-7-aza-bicyclo[2.2.1]heptane-2-carboxylic acid methyl ester racemate
CAS No.:688790-06-9
Molecular Formula:C13H21NO4
Molecular Weight:255.31
Hs Code.:2933990090
Mol file:688790-06-9.mol

Synonyms:7-tert-Butyl 2-methyl 7-azabicyclo[2.2.1]heptane-2,7-dicarboxylate;7-O-tert-butyl 3-O-methyl 7-azabicyclo[2.2.1]heptane-3,7-dicarboxylate;7-Aza-bicyclo[2.2.1]heptane-2,7-dicarboxylic acid 7-tert-butyl ester 2-methyl ester;7-Azabicyclo[2.2.1]heptane-2,7-dicarboxylic acid, 7-(1,1-dimethylethyl) 2-methyl ester;exo-7-(tert-butoxycarbonyl)-7-aza-bicyclo[2.2.1]heptane-2-carboxylic acid methyl ester racemate

Suppliers and Price of exo-7-(tert-butoxycarbonyl)-7-aza-bicyclo[2.2.1]heptane-2-carboxylic acid methyl ester racemate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
7-tert-Butyl2-methyl7-azabicyclo[2.2.1]heptane-2,7-dicarboxylate 95+%
1g
$ 650.00

Chemenu
7-(tert-butyl)2-methyl7-azabicyclo[2.2.1]heptane-2,7-dicarboxylate 95%
1g
$ 729.00

American Custom Chemicals Corporation
7-TERT-BUTYL-2-METHYL-7-AZABICYCLO[2.2.1]HEPTANE-2,7-DICARBOXYLATE 95.00%
5MG
$ 502.69

Total 10 raw suppliers

Chemical Property of exo-7-(tert-butoxycarbonyl)-7-aza-bicyclo[2.2.1]heptane-2-carboxylic acid methyl ester racemate

Chemical Property:

Boiling Point:323.5±25.0 °C(Predicted)
PKA:-2.19±0.40(Predicted)
PSA：55.84000
Density:1.154±0.06 g/cm3(Predicted)
LogP:1.88530

Purity/Quality:

99% ^*data from raw suppliers

7-tert-Butyl2-methyl7-azabicyclo[2.2.1]heptane-2,7-dicarboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of exo-7-(tert-butoxycarbonyl)-7-aza-bicyclo[2.2.1]heptane-2-carboxylic acid methyl ester racemate

There total 2 articles about exo-7-(tert-butoxycarbonyl)-7-aza-bicyclo[2.2.1]heptane-2-carboxylic acid methyl ester racemate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 502506-71-0
7-tert-butyl 2-ethyl 3-bromo-7-azabicyclo[2.2.1]hepta-2,5-diene-2,7-dicarboxylate

: 688790-06-9,197080-73-2
7-tert-butyl 2-methyl 7-azabicyclo[2.2.1]heptane-2,7-dicarboxylate

Guidance literature:: With palladium on activated charcoal; hydrogen; In ethanol; at 20 ℃; for 3h;

Reference yield:

: 181873-33-6
3-bromo-7-aza-bicyclo[2.2.1]hepta-2,5-diene-2,7-dicarboxylic acid 7-tert-butyl ester 2-methyl ester

: 688790-06-9,197080-73-2
7-tert-butyl 2-methyl 7-azabicyclo[2.2.1]heptane-2,7-dicarboxylate

Guidance literature:: With palladium 10% on activated carbon; hydrogen; triethylamine; In methanol; at 20 ℃; for 7h;
DOI:10.1002/cmdc.201900398

Reference yield:

: 688790-06-9,197080-73-2
7-tert-butyl 2-methyl 7-azabicyclo[2.2.1]heptane-2,7-dicarboxylate

: benzyl 2-(hydroxymethyl)-7-azabicyclo [2.2.1] heptane-7-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride / 1,4-dioxane / 2 h / 0 - 20 °C

2: triethylamine / dichloromethane / 14 h / 0 - 20 °C

3: lithium borohydride / tetrahydrofuran / 12 h / 0 - 60 °C

With hydrogenchloride; lithium borohydride; triethylamine; In tetrahydrofuran; 1,4-dioxane; dichloromethane;