tert-butyl 1-aMino-7-azaspiro[3.5]nonane-7-carboxylate HCl

Base Information

• Chemical Name: tert-butyl 1-aMino-7-azaspiro[3.5]nonane-7-carboxylate HCl
• CAS No.: 1100748-78-4
• Molecular Formula: C13H25ClN2O2
• Molecular Weight: 276.807
• Hs Code.: 2933990090
• Mol file: 1100748-78-4.mol

Synonyms:tert-butyl 1-amino-7-azaspiro[3.5]nonane-7-carboxylate hydrochloride;Y7036;

Chemical Property of tert-butyl 1-aMino-7-azaspiro[3.5]nonane-7-carboxylate HCl

Chemical Property:

• PSA: 55.56000
• LogP: 3.56500

Purity/Quality:

98%,99%, ^*data from raw suppliers

tert-Butyl1-Amino-7-azaspiro[3.5]nonane-7-carboxylateHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of tert-butyl 1-aMino-7-azaspiro[3.5]nonane-7-carboxylate HCl

There total 1 articles about tert-butyl 1-aMino-7-azaspiro[3.5]nonane-7-carboxylate HCl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

tert-butyl 1-amino-7-azaspiro[3.5]nonane-7-carboxylate (1100748-84-2) → 1-amino-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester hydrochloride (1100748-78-4)

Guidance literature:

With hydrogenchloride; In diethyl ether;

DOI:10.1021/jo802456w

Reference yield: 76.0%

1-amino-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester hydrochloride (1100748-78-4) + 4-[3-(2H-1,2,3-triazol-2-yl)phenylamino]-6-amino-2-(methylmercapto)pyrimidine-5-carbonitrile → 1-[4-[3-(2H-1,2,3-triazol-2-yl)phenylamino]-6-amino-5-cyanopyrimidin-2-ylamino]-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 4h;

upstream raw materials:

tert-butyl 1-amino-7-azaspiro[3.5]nonane-7-carboxylate

Refernces