Periglaucine B

Base Information

• Chemical Name: Periglaucine B
• CAS No.: 1025023-05-5
• Molecular Formula: C20H23NO6
• Molecular Weight: 373.39972
• Mol file: 1025023-05-5.mol

Synonyms:Periglaucine B;(7beta,8beta,10beta)-8,10-Epoxy-7,8-dimethoxy-17-methyl-2,3-[methylenebis(oxy)]-hasubanan-6-one

Chemical Property of Periglaucine B

Chemical Property:

• PSA: 66.46000
• LogP: 1.47080

Purity/Quality:

98% ^*data from raw suppliers

PeriglaucineB 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Periglaucine B

There total 1 articles about Periglaucine B which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C20H23NO6 → (7β,8β,10β)-8,10-epoxy-7,8-dimethoxy-2,3-[methylenebis(oxy)]-17-methyl-6-oxohasubanan (1025023-05-5)

Guidance literature:

With formic acid; Inert atmosphere;

DOI:10.1021/jo401889b

Reference yield:

(7β,8β,10β)-8,10-epoxy-7,8-dimethoxy-2,3-[methylenebis(oxy)]-17-methyl-6-oxohasubanan (1025023-05-5) → (+)-oxostephabenine (99964-46-2)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium permanganate / water; acetone / 3 h / 0 - 24 °C / Inert atmosphere

2: sodium tetrahydroborate / ethanol / 0.25 h / 0 °C / Inert atmosphere

3: pyridine / 3 h / 0 °C / Inert atmosphere

With pyridine; sodium tetrahydroborate; potassium permanganate; In ethanol; water; acetone;

DOI:10.1021/jo401889b

Reference yield:

(7β,8β,10β)-8,10-epoxy-7,8-dimethoxy-2,3-[methylenebis(oxy)]-17-methyl-6-oxohasubanan (1025023-05-5) → (-)-stephabenine (87853-56-3)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium tetrahydroborate / ethanol / 0.25 h / 0 °C / Inert atmosphere

2: pyridine / 3 h / 0 °C / Inert atmosphere

With pyridine; sodium tetrahydroborate; In ethanol;

DOI:10.1021/jo401889b

Downstream raw materials:

(+)-N,O-dimethyloxostephine

(+)-oxostephabenine

(-)-prostephanaberrine

(-)-stephanaberrine

Refernces