25i-NBF

Base Information

• Chemical Name: 25i-NBF
• CAS No.: 919797-21-0
• Molecular Formula: C₁₇H₁₉FINO₂
• Molecular Weight: 415.246
• Mol file: 919797-21-0.mol

Synonyms:25I-NBF;

Chemical Property of 25i-NBF

Chemical Property:

• Appearance/Colour: white powder
• PSA: 30.49000
• Density: 1.469±0.06 g/cm3 (20 oC 760 Torr)
• LogP: 4.17070

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 25i-NBF

There total 2 articles about 25i-NBF which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C17H17FINO2 → 2-(4-Iodo-2,5-dimethoxyphenyl)-N-[(2-fluorophenyl)methyl] ethanamine (919797-21-0)

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 20 ℃; for 0.5h;

DOI:10.1021/cn400216u

Reference yield:

4-iodo-2,5-dimethoxy-β-phenethylamine hydrochloride (64584-32-3) + 2-Fluorobenzaldehyde (446-52-6) → 2-(4-Iodo-2,5-dimethoxyphenyl)-N-[(2-fluorophenyl)methyl] ethanamine (919797-21-0)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / ethanol / 20 °C

2: sodium tetrahydroborate / ethanol / 0.5 h / 20 °C

With sodium tetrahydroborate; triethylamine; In ethanol;

DOI:10.1021/cn400216u

upstream raw materials:

4-iodo-2,5-dimethoxy-β-phenethylamine hydrochloride

2-Fluorobenzaldehyde