15-Keto Travoprost

Base Information

Chemical Name:15-Keto Travoprost
CAS No.:404830-45-1
Molecular Formula:C26H33F3O6
Molecular Weight:498.53200
Hs Code.:
European Community (EC) Number:690-685-8
UNII:4U2P9U9Z66
Wikidata:Q27260497
Mol file:404830-45-1.mol

Synonyms:15-Keto Travoprost;404830-45-1;15-keto Fluprostenol isopropyl ester;15-Oxo travoprost;UNII-4U2P9U9Z66;4U2P9U9Z66;(Z)-Isopropyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((E)-3-oxo-4-(3-(trifluoromethyl)phenoxy)but-1-en-1-yl)cyclopentyl)hept-5-enoate;propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoate;Travoprost impurity, 15-keto derivative- [USP];(5Z,13E)-(9S,11R)-9,11,-Dihydroxy-15-oxo-16-(m-trifluoromethylphenoxy)-17,18,19,20-tetranor-5,13-prostadienoic acid, isopropyl ester;5-Heptenoic acid, 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E)-3-oxo-4-(3-(trifluoromethyl)phenoxy)-1-buten-1-yl)cyclopentyl)-, 1-methylethyl ester, (5Z)-;SCHEMBL16938459;CHEBI:168868;HMS3648H20;15-Ketofluprostenol isopropyl ester;AKOS025295300;PD021281;HY-116617;CS-0066079;SR-01000946510;J-502637;SR-01000946510-1;Q27260497;TRAVOPROST IMPURITY, 15-KETO DERIVATIVE- [USP IMPURITY];15-Oxo-9.alpha.,11.alpha.-dihydroxy-16-(3-(trifluoromethyl)phenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid, isopropyl ester;propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxo-4-[3-(triluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoate

Suppliers and Price of 15-Keto Travoprost

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
15-KetoTravoprost
1mg
$ 80.00

Cayman Chemical
15-keto Fluprostenol isopropyl ester ≥98%
5mg
$ 346.00

Cayman Chemical
15-keto Fluprostenol isopropyl ester ≥98%
1mg
$ 78.00

Cayman Chemical
15-keto Fluprostenol isopropyl ester ≥98%
25mg
$ 1344.00

Cayman Chemical
15-keto Fluprostenol isopropyl ester ≥98%
10mg
$ 615.00

American Custom Chemicals Corporation
(+/-)-15-OXO-9ALPHA,11ALPHA-DIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER 95.00%
5MG
$ 505.81

Total 43 raw suppliers

Chemical Property of 15-Keto Travoprost

Chemical Property:

Boiling Point:577.5±50.0 °C(Predicted)
PKA:14.38±0.70(Predicted)
PSA：93.06000
Density:1.242±0.06 g/cm3(Predicted)
LogP:4.63560
Storage Temp.:Amber Vial, -20°C Freezer, Under inert atmosphere
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:4.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:13
Exact Mass:498.22292325
Heavy Atom Count:35
Complexity:733

Purity/Quality:

98%, ^*data from raw suppliers

15-KetoTravoprost ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)OC(=O)CCCC=CCC1C(CC(C1C=CC(=O)COC2=CC=CC(=C2)C(F)(F)F)O)O
Isomeric SMILES:CC(C)OC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H]([C@@H]1/C=C/C(=O)COC2=CC=CC(=C2)C(F)(F)F)O)O
Uses 15-Keto Travoprost is an impurity of the selective FP prostaglandin receptor agonist Travoprost (T715600) used as an ocularly applied intraocular pressure reducing agent.

Technology Process of 15-Keto Travoprost

There total 1 articles about 15-Keto Travoprost which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.4%