N-Octadecanoyl-D-valine

Base Information

• Chemical Name: N-Octadecanoyl-D-valine
• CAS No.: 14379-33-0
• Molecular Formula: C₂₃H₄₅NO₃
• Molecular Weight: 383.615
• Mol file: 14379-33-0.mol

Synonyms:N-stearoyl-L-valine;N-Stearyl-L-valin;N-stearoylvaline;N-octadecanoyl-valine;N-Octadecanoyl-D-valine;

Chemical Property of N-Octadecanoyl-D-valine

Chemical Property:

• PSA: 66.40000
• LogP: 6.86420

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: suzuki reaction

Technology Process of N-Octadecanoyl-D-valine

There total 6 articles about N-Octadecanoyl-D-valine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

stearic acid N-hydroxysuccinimide ester (14464-32-5) + L-valine (72-18-4,25609-85-2,7004-03-7,921-10-8) → N-octadecanoyl-L-valine (14379-33-0,83871-22-1,14379-32-9)

Guidance literature:

With triethylamine; In ethanol; water; at 60 - 80 ℃; for 20h;

DOI:10.1039/c5ra10209j

Reference yield:

C24H47NO3 (92072-22-5) → N-octadecanoyl-L-valine (14379-33-0,83871-22-1,14379-32-9)

Guidance literature:

With sodium hydroxide;

DOI:10.1016/j.ejmech.2009.02.028

Reference yield:

stearic acid (57-11-4) → N-octadecanoyl-L-valine (14379-33-0,83871-22-1,14379-32-9)

Guidance literature:

Multi-step reaction with 2 steps

1: dicyclohexyl-carbodiimide / ethyl acetate / 6 h

2: triethylamine / water; ethanol / 20 h / 60 - 80 °C

With triethylamine; dicyclohexyl-carbodiimide; In ethanol; water; ethyl acetate;

DOI:10.1039/c5ra10209j

upstream raw materials:

C₂₄H₄₇NO₃

L-Valine methyl ester

stearic acid

stearic acid N-hydroxysuccinimide ester