4-Bromo-6-chloroquinoline

Base Information

• Chemical Name: 4-Bromo-6-chloroquinoline
• CAS No.: 1070879-30-9
• Molecular Formula: C9H5BrClN
• Molecular Weight: 242.4997
• Hs Code.: 2933499090
• Mol file: 1070879-30-9.mol

Synonyms:4-Bromo-6-chloroquinoline

Chemical Property of 4-Bromo-6-chloroquinoline

Chemical Property:

• Boiling Point: 331.3±22.0 °C(Predicted)
• PKA: 2.58±0.16(Predicted)
• PSA: 12.89000
• Density: 1.673
• LogP: 3.65070
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Bromo-6-chloroquinoline ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 25-41
• Safety Statements: 26-39-45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Bromo-6-chloroquinoline

There total 2 articles about 4-Bromo-6-chloroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

4,6-dichloroquinoline (4203-18-3) → 4-bromo-6-chloroquinoline (1070879-30-9)

Guidance literature:

With trimethylsilyl bromide; propiononitrile; at 100 ℃; for 16h; Time; Sealed tube;

Reference yield:

→ 4-bromo-6-chloroquinoline (1070879-30-9)

Guidance literature:

upstream raw materials:

4,6-dichloroquinoline

Refernces

• 1、 -. "Process for piperidine intermediates for quinine, quinidine and analogs thereof". . . Retrieved 2008/06/13.