Propanamide, 3-amino-N-phenyl-, monohydrochloride

Base Information

• Chemical Name: Propanamide, 3-amino-N-phenyl-, monohydrochloride
• CAS No.: 115022-95-2
• Molecular Formula: C9H12N2O.ClH
• Molecular Weight: 200.66532
• Hs Code.: 2924299090
• Mol file: 115022-95-2.mol

Synonyms:3-AMINO-N-PHENYLPROPANAMIDE HYDROCHLORIDE;BB_SC-8136;

Chemical Property of Propanamide, 3-amino-N-phenyl-, monohydrochloride

Chemical Property:

• PSA: 55.12000
• LogP: 2.54920

Purity/Quality:

97% ^*data from raw suppliers

n~1~-Phenyl-β-alaninamideHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Propanamide, 3-amino-N-phenyl-, monohydrochloride

There total 3 articles about Propanamide, 3-amino-N-phenyl-, monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

benzyl (3-oxo-3-(phenylamino)propyl)carbamate (115022-93-0) → H-β-Ala-NH-Phenyl*HCl (115022-95-2)

Guidance literature:

With hydrogenchloride; hydrogen; palladium; In methanol;

Reference yield:

aniline (62-53-3) → H-β-Ala-NH-Phenyl*HCl (115022-95-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent

2: 88 percent / hydrogen, hydrogen chloride / palladium black / methanol

With hydrogenchloride; hydrogen; palladium; In methanol;

Reference yield:

tert-butyl [3-oxo-3-(phenylamino)propyl]carbamate (874942-22-0) → H-β-Ala-NH-Phenyl*HCl (115022-95-2)

Guidance literature:

With hydrogenchloride; In dichloromethane; at 0 - 5 ℃; for 2h;

DOI:10.1055/s-0032-1308982

upstream raw materials:

benzyl (3-oxo-3-(phenylamino)propyl)carbamate

aniline

tert-butyl [3-oxo-3-(phenylamino)propyl]carbamate

Downstream raw materials:

N-benzoyl-β-alanine anilide