8-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine

Base Information

Chemical Name:8-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine
CAS No.:140911-31-5
Molecular Formula:C6H2ClF3N4
Molecular Weight:222.557
Hs Code.:2933990090
DSSTox Substance ID:DTXSID90436910
Wikidata:Q82252253
Mol file:140911-31-5.mol

Synonyms:140911-31-5;8-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine;8-chloro-3-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyrazine;1,2,4-TRIAZOLO[4,3-A]PYRAZINE, 8-CHLORO-3-(TRIFLUOROMETHYL)-;SCHEMBL3132632;DTXSID90436910;AKOS011652596;AB53044;8-Chloro-3-(trifluoromethyl) [1,2,4]triazolo[4,3-a]pyrazine

Suppliers and Price of 8-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
8-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine 95+%
1g
$ 412.00

American Custom Chemicals Corporation
8-CHLORO-3-(TRIFLUOROMETHYL)-1,2,4-TRIAZOLO[4,3-A]PYRAZINE 95.00%
5MG
$ 495.65

Alichem
8-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine
1g
$ 429.24

Alichem
8-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine
250mg
$ 178.50

Total 11 raw suppliers

Chemical Property of 8-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine

Chemical Property:

PSA：43.08000
LogP:1.79650
Storage Temp.:2-8°C
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:0
Exact Mass:221.9920083
Heavy Atom Count:14
Complexity:224

Purity/Quality:

98%min ^*data from raw suppliers

8-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN2C(=NN=C2C(F)(F)F)C(=N1)Cl

Technology Process of 8-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine

There total 3 articles about 8-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine-8-ol

: 140911-31-5
8-chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine

Guidance literature:: With N,N-dimethyl-formamide; trichlorophosphate; at 100 ℃; for 4h;

Reference yield:

: 877402-74-9
3-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyrazine 7-oxide

: 140911-31-5
8-chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine

Guidance literature:: With trichlorophosphate; for 2.5h; Heating / reflux;

Reference yield:

: C₈H₃ClF₆N₄O₂

: 140911-31-5
8-chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine

Guidance literature:: Multi-step reaction with 2 steps

1: polyphosphoric acid / 80 °C

2: trichlorophosphate / 110 °C

With trichlorophosphate;