4-(Piperazin-1-ylmethyl)benzonitrile hydrochloride

Base Information

Chemical Name:4-(Piperazin-1-ylmethyl)benzonitrile hydrochloride
CAS No.:1158548-82-3
Molecular Formula:C12H16ClN3
Molecular Weight:237.729
Hs Code.:2933599090
DSSTox Substance ID:DTXSID70589413
Mol file:1158548-82-3.mol

Synonyms:1158548-82-3;4-(piperazin-1-ylmethyl)benzonitrile hydrochloride;4-(PIPERAZINOMETHYL)BENZONITRILE, HYDROCHLORIDE;4-Piperazin-1-ylmethyl-benzonitrile hydrochloride;4-(piperazin-1-ylmethyl)benzonitrile;hydrochloride;4-[(piperazin-1-yl)methyl]benzonitrile hydrochloride;DTXSID70589413;AKOS024464273;DB-306115;CS-0249719;EN300-44949;F80180;4-[(Piperazin-1-yl)methyl]benzonitrile--hydrogen chloride (1/1)

Suppliers and Price of 4-(Piperazin-1-ylmethyl)benzonitrile hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(Piperazinomethyl)benzonitrile,Hydrochloride
1g
$ 140.00

Chemenu
4-(piperazin-1-ylmethyl)benzonitrilehydrochloride 95%
500mg
$ 225.00

American Custom Chemicals Corporation
4-(PIPERAZIN-1-YLMETHYL)BENZONITRILE HYDROCHLORIDE 95.00%
1G
$ 692.46

American Custom Chemicals Corporation
4-(PIPERAZIN-1-YLMETHYL)BENZONITRILE HYDROCHLORIDE 95.00%
5G
$ 1114.58

American Custom Chemicals Corporation
4-(PIPERAZIN-1-YLMETHYL)BENZONITRILE HYDROCHLORIDE 95.00%
2.5G
$ 932.60

Acrotein
4-(Piperazin-1-ylmethyl)benzonitrileHCl 97%
5g
$ 750.00

Total 9 raw suppliers

Chemical Property of 4-(Piperazin-1-ylmethyl)benzonitrile hydrochloride

Chemical Property:

Melting Point:285-308°C dec.
PSA：39.06000
LogP:2.03218
Solubility.:Water
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:237.1032752
Heavy Atom Count:16
Complexity:229

Purity/Quality:

97% ^*data from raw suppliers

4-(Piperazinomethyl)benzonitrile,Hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1)CC2=CC=C(C=C2)C#N.Cl
Uses 4-(Piperazinomethyl)benzonitrile, Hydrochloride (cas# 1158548-82-3) is a compound useful in organic synthesis.

Technology Process of 4-(Piperazin-1-ylmethyl)benzonitrile hydrochloride

There total 2 articles about 4-(Piperazin-1-ylmethyl)benzonitrile hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 849237-14-5
4-(4-cyanobenzyl)piperazine-1-carboxylic acid tert-butyl ester

: 1158548-82-3
4-[(piperazin-1-yl)methyl]benzonitrile dihydrochloride

Guidance literature:: With hydrogenchloride; In chloroform; ethyl acetate; at 20 ℃; for 72h;
DOI:10.1248/CPB.C20-00015

Reference yield:

: 105-07-7
4-cyanobenzaldehyde

: 1158548-82-3
4-[(piperazin-1-yl)methyl]benzonitrile dihydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetic acid / dichloromethane / 0.5 h / 20 °C

1.2: 3 h / 20 °C

2.1: hydrogenchloride / ethyl acetate; chloroform / 72 h / 20 °C

With hydrogenchloride; acetic acid; In dichloromethane; chloroform; ethyl acetate;
DOI:10.1248/CPB.C20-00015