4-(6-Chloro-pyriMidin-4-ylaMino)-piperidine-1-carboxylic acid tert-butyl ester, 98+% C14H21ClN4O2, MW: 312.80

Base Information

• Chemical Name: 4-(6-Chloro-pyriMidin-4-ylaMino)-piperidine-1-carboxylic acid tert-butyl ester, 98+% C14H21ClN4O2, MW: 312.80
• CAS No.: 939986-76-2
• Molecular Formula: C₁₄H₂₁ClN₄O₂
• Molecular Weight: 312.799
• Hs Code.: 2933990090
• Mol file: 939986-76-2.mol

Synonyms:tert-butyl 4-[(6-chloropyrimidin-4-yl)amino]piperidinecarboxylate;tert-Butyl 4-((6-chloropyrimidin-4-yl)amino)piperidine-1-carboxylate;4-(6-Chloro-pyrimidin-4-ylamino)-piperidine-1-carboxylic acid tert-butyl ester;

Chemical Property of 4-(6-Chloro-pyriMidin-4-ylaMino)-piperidine-1-carboxylic acid tert-butyl ester, 98+% C14H21ClN4O2, MW: 312.80

Chemical Property:

• PSA: 67.35000
• Density: 1.261
• LogP: 2.95230

Purity/Quality:

99% ^*data from raw suppliers

tert-Butyl 4-[(6-chloropyrimidin-4-yl)amino]piperidine-1-carboxylate >97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(6-Chloro-pyriMidin-4-ylaMino)-piperidine-1-carboxylic acid tert-butyl ester, 98+% C14H21ClN4O2, MW: 312.80

There total 1 articles about 4-(6-Chloro-pyriMidin-4-ylaMino)-piperidine-1-carboxylic acid tert-butyl ester, 98+% C14H21ClN4O2, MW: 312.80 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

4,6-dichloropyrimidine (1193-21-1) + 1-(tert-butoxycarbonyl)-4-aminopiperidine (87120-72-7) → tert-butyl 4-(6-chloropyrimidin-4-ylamino)piperidine-1-carboxylate (939986-76-2)

Guidance literature:

With triethylamine; In ethanol; at 80 ℃; for 16h; Solvent; Temperature;

DOI:10.1016/j.bmc.2021.116208

upstream raw materials:

4,6-dichloropyrimidine

1-(tert-butoxycarbonyl)-4-aminopiperidine