2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride

Base Information

Chemical Name:2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride
CAS No.:22204-88-2
Molecular Formula:C₁₆H₂₅NO₂*ClH
Molecular Weight:299.841
Hs Code.:2922509090
European Community (EC) Number:683-089-4
ChEMBL ID:CHEMBL1237065
Mol file:22204-88-2.mol

2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride

Synonyms:Adolonta;Amadol;Biodalgic;Biokanol;Contramal;Jutadol;K 315;K-315;K315;MTW Tramadol;MTW-Tramadol;MTWTramadol;Nobligan;Prontofort;Ranitidin 1A Pharma;Takadol;Theradol;Tiral;Topalgic;Tradol;Tradol Puren;Tradol-Puren;TradolPuren;Tradonal;Tralgiol;Trama 1A Pharma;Trama AbZ;Trama Dorsch;Trama KD;Trama-Dorsch;Tramabeta;Tramadin;Tramadoc;Tramadol;Tramadol 1A;Tramadol acis;Tramadol AL;Tramadol Asta Medica;Tramadol Basics;Tramadol Bayvit;Tramadol Bexal;Tramadol Cinfa;Tramadol Dolgit;Tramadol Edigen;Tramadol Hameln;Tramadol Heumann;Tramadol Hydrochloride;Tramadol Kern;Tramadol Lichtenstein;Tramadol Lindo;Tramadol Mabo;Tramadol Normon;Tramadol PB;Tramadol Ratiopharm;Tramadol Stada;Tramadol-Dolgit;Tramadol-Hameln;Tramadol-ratiopharm;TramadolDolgit;TramadolHameln;Tramadolor;Tramadolratiopharm;TramaDorsch;Tramadura;Tramagetic;Tramagit;Tramake;Tramal;Tramex;Tramundin;Trasedal;Ultram;Xymel 50;Zamudol;Zumalgic;Zydol;Zytram

This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of 2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride

Chemical Property:

Vapor Pressure:1.02E-06mmHg at 25°C
Melting Point:171°C
Boiling Point:388.1°C at 760 mmHg
Flash Point:188.5°C
PSA：32.70000
Density:1.047g/cm³
LogP:3.43660
Storage Temp.:2-8°C
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:299.1652068
Heavy Atom Count:20
Complexity:282

Purity/Quality:

Safty Information:

Pictogram(s): F,T
Hazard Codes:F,T
Statements: 11-23/24/25-39/23/24/25
Safety Statements: 16-36/37-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CC1CCCCC1(C2=CC(=CC=C2)OC)O.Cl
Recent EU Clinical Trials:Tramadol iv. : influence of dose and dose intervals on therapeutic accuracy and side effects when used for postoperative pain relief in ambulatory surgery
Uses An Analgesic
Therapeutic Function Analgesic
Clinical Use Analgesic
Drug interactions Potentially hazardous interactions with other drugs Analgesics: possible opioid withdrawal with buprenorphine and pentazocine. Anticoagulants: enhances effect of coumarins. Antidepressants: possibly increased serotonergic effects with duloxetine, mirtazapine or venlafaxine; possible CNS excitation or depression with MAOIs and moclobemide - avoid with MAOIs as increased risk of serotonergic effects and convulsions; increased risk of CNS toxicity with SSRIs or tricyclics. Antiepileptics: effect reduced by carbamazepine. Antihistamines: increased sedative effects with sedating antihistamines. Antipsychotics: enhanced hypotensive and sedative effects; increased risk of convulsions. Atomoxetine: increased risk of convulsions. Dapoxetine: possible increased risk of serotonergic effects - avoid. Dopaminergics: avoid with selegiline. Nalmefene: avoid concomitant use. Sodium oxybate: enhanced effect of sodium oxybate - avoid concomitant use.

Technology Process of 2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride

There total 3 articles about 2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%