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Technology Process of Palonosetron hydrochloride, (3R)-

Palonosetron hydrochloride, (3R)-

Base Information
  • Chemical Name:Palonosetron hydrochloride, (3R)-
  • CAS No.:135729-76-9
  • Molecular Formula:C19H24N2O.ClH
  • Molecular Weight:332.8676
  • Hs Code.:2933790002
  • UNII:1J5X5HPB4C
  • ChEMBL ID:CHEMBL545717
  • Mol file:135729-76-9.mol
Palonosetron hydrochloride, (3R)-

Synonyms:2-(1-azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one;2-QHBIQO;Aloxi;palonosetron;palonosetron hydrochloride;Palonosetron, (3R)-;palonosetron, (R-(R*,R*))-isomer;palonosetron, (R-(R*,S*))-isomer;palonosetron, (S-(R*,S*))-isomer;RS 25233 197;RS 25233 198;RS 25233-197;RS 25233-198;RS 25233197;RS 25233198;RS 25259;RS 25259 197;RS 25259 198;RS 25259-197;RS 25259-198;RS 25259197;RS 25259198;RS-25233-197;RS-25233-198;RS-25259;RS-25259-197;RS-25259-198;RS25233197;RS25233198;RS25259;RS25259197;RS25259198

Suppliers and Price of Palonosetron hydrochloride, (3R)-
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • (S,R)-PalonosetronHydrochlorideContainsupto~35%(R,R)-isomer
  • 5mg
  • $ 185.00
  • Crysdot
  • (S)-2-((1S,3R,4S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-onehydrochloride 97%
  • 1g
  • $ 1131.00
  • Chemenu
  • (S)-2-((1S,3R,4S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-onehydrochloride 97%
  • 1g
  • $ 1066.00
  • American Custom Chemicals Corporation
  • (S,R)-PALONOSETRON HYDROCHLORIDE 95.00%
  • 5MG
  • $ 866.80
Total 19 raw suppliers
Chemical Property of Palonosetron hydrochloride, (3R)-
Chemical Property:
  • PSA：23.55000 
  • LogP:3.33430 
  • Storage Temp.:Hygroscopic, Refrigerator, under inert atmosphere 
  • Solubility.:DMSO (Slightly), Methanol (Slightly), Water (Slightly) 
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:2
  • Rotatable Bond Count:1
  • Exact Mass:332.1655411
  • Heavy Atom Count:23
  • Complexity:456
Purity/Quality:

97% *data from raw suppliers

(S,R)-PalonosetronHydrochlorideContainsupto~35%(R,R)-isomer *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:C1CC2CN(C(=O)C3=CC=CC(=C23)C1)C4CN5CCC4CC5.Cl
  • Isomeric SMILES:C1C[C@@H]2CN(C(=O)C3=CC=CC(=C23)C1)[C@H]4CN5CCC4CC5.Cl
  • Uses The (S,R)-enantiomer of Palonosetron (P165800), a potent and selective antagonist, with 5-HT3 receptor The (S,R)-enantiomer of Palonosetron (P165800), a potent and selective antagonist, with 5-HT3 receptor in vitro. An impurity of Palonosetron.
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