4-(1-bromoethyl)-6-(4-chlorophenylthio)-5-fluoropyrimidine

Base Information

Chemical Name:4-(1-bromoethyl)-6-(4-chlorophenylthio)-5-fluoropyrimidine
CAS No.:1112937-26-4
Molecular Formula:C12H9BrClFN2S
Molecular Weight:347.638
Hs Code.:
Mol file:1112937-26-4.mol

Synonyms:4-(1-broMoethyl)-6-(4-chlorophenylthio)-5-fluoropyriMidine;Pyrimidine, 4-(1-bromoethyl)-6-[(4-chlorophenyl)thio]-5-fluoro-;4-(1-Bromoethyl)-6-(4-chlorophenylthio)-5-fluoropyrimidine (VBT)

Suppliers and Price of 4-(1-bromoethyl)-6-(4-chlorophenylthio)-5-fluoropyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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price

Total 14 raw suppliers

Chemical Property of 4-(1-bromoethyl)-6-(4-chlorophenylthio)-5-fluoropyrimidine

Chemical Property:

Boiling Point:406.9±45.0 °C(Predicted)
PKA:-1.72±0.46(Predicted)
PSA：51.08000
Density:1.63±0.1 g/cm3(Predicted)
LogP:4.87620

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

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Hazard Codes:

MSDS Files:

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Technology Process of 4-(1-bromoethyl)-6-(4-chlorophenylthio)-5-fluoropyrimidine

There total 1 articles about 4-(1-bromoethyl)-6-(4-chlorophenylthio)-5-fluoropyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 1112937-23-1
4-(4-chloro-phenylsulfanyl)-6-ethyl-5-fluoropyrimidine

: 1112937-26-4
4-(1-bromo-ethyl)-6-(4-chloro-phenylsulfanyl)-5-fluoropyrimidine

Guidance literature:: With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In 1,1-dichloroethane; for 2h; Heating / reflux;

Reference yield: 72.8%

: 1112937-26-4
4-(1-bromo-ethyl)-6-(4-chloro-phenylsulfanyl)-5-fluoropyrimidine

: 86404-63-9
1-(2,4-difluorophenyl)-2-(1H-1,2,4-triazolyl)ethanone

: (2R,3S)/(2S,3R)-3-[6-(4-chloro-phenylsulfanyl)-5-fluoro-pyrimidine-4-yl]-2-(2,4-difluoro-phenyl)-1-[1,2,4]triazol-1-yl-butane-2-ol

Guidance literature:: 4-(1-bromo-ethyl)-6-(4-chloro-phenylsulfanyl)-5-fluoropyrimidine; 1-(2,4-difluorophenyl)-2-(1H-1,2,4-triazolyl)ethanone; With hydrogenchloride; lead; iodine; zinc; In tetrahydrofuran; water; at 5 - 25 ℃; for 2 - 3h;

With sodium hydrogencarbonate; In water; ethyl acetate; pH=7.6; Product distribution / selectivity;