4-Hydroxypicolinaldehyde

Base Information

• Chemical Name: 4-Hydroxypicolinaldehyde
• CAS No.: 933030-90-1
• Molecular Formula: C₆H₅NO₂
• Molecular Weight: 123.111
• DSSTox Substance ID: DTXSID401267497
• Nikkaji Number: J2.433.566F
• Mol file: 933030-90-1.mol

Synonyms:4-hydroxypicolinaldehyde;1060809-85-9;4-HYDROXY-PYRIDINE-2-CARBALDEHYDE;933030-90-1;4-Oxo-1,4-dihydropyridine-2-carbaldehyde;4-OXO-1H-PYRIDINE-2-CARBALDEHYDE;4-hydroxypyridine-2-carbaldehyde;1,4-DIHYDRO-4-OXO-2-PYRIDINECARBOXALDEHYDE;SCHEMBL14998813;4-hydroxy-2-pyridinecarboxaldehyde;DTXSID401267497;2-Pyridinecarboxaldehyde, 4-hydroxy;MFCD13189290;AKOS006378846;AKOS016005707;AB68125;SB30438;AM20050642;CS-0339546

Chemical Property of 4-Hydroxypicolinaldehyde

Chemical Property:

• XLogP3: -0.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 123.032028402
• Heavy Atom Count: 9
• Complexity: 203

Purity/Quality:

4-Oxo-1,4-dihydropyridine-2-carbaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CNC(=CC1=O)C=O

Technology Process of 4-Hydroxypicolinaldehyde

There total 1 articles about 4-Hydroxypicolinaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(hydroxymethyl)-1,4-dihydropyridine-4-one (860411-74-1,933030-89-8) → 4-oxo-1,4-dihydro-pyridine-2-carbaldehyde (933030-90-1) + 2-(dihydroxymethyl)-1,4-dihydropyridine-4-one

Guidance literature:

With manganese (IV) dioxide; In methanol; dichloromethane; acetone; at 60 ℃; for 4h; Title compound not separated from byproducts.;

DOI:10.1002/jhet.5570440124

upstream raw materials:

2-(hydroxymethyl)-1,4-dihydropyridine-4-one