(2S,4S)-1-CBZ-4-aMino Pyrrolidine-2-carboxylic acid Methylester-HCl

Base Information

• Chemical Name: (2S,4S)-1-CBZ-4-aMino Pyrrolidine-2-carboxylic acid Methylester-HCl
• CAS No.: 1212395-57-7
• Molecular Formula: C₁₄H₁₈N₂O₄*ClH
• Molecular Weight: 314.769
• Hs Code.: 2933998090
• Mol file: 1212395-57-7.mol

Synonyms:METHYL (2S, 4S)-4-AMINO-1-CBZ-PYRROLIDINE-2-CARBOXYLATE HCL;Cbz-(2S,4S)-4-amino-proline methyl ester, hydrochloride (1:1);(2S, 4S)-4-Amino-1-[benzyloxycarbonyl]pyrrolidine-2-methylcarboxylate, HCl;1-Benzyl 2-methyl (2S,4S)-4-aminopyrrolidine-1,2-dicarboxylate hydrochloride;rel-1-Benzyl2-methyl(2S,4S)-4-aminopyrrolidine-1,2-dicarboxylatehydrochloride;(2S,4S)-4-Amino-1-[(benzyloxy)carbonyl]-2-(methoxycarbonyl)pyrrolidine hydrochloride, cis-4-Amino-L-proline methyl ester, N-CBZ protected hydrochloride

Chemical Property of (2S,4S)-1-CBZ-4-aMino Pyrrolidine-2-carboxylic acid Methylester-HCl

Chemical Property:

• PSA: 81.86000
• LogP: 2.33800

Purity/Quality:

99% ^*data from raw suppliers

1-Benzyl 2-methyl (2S,4S)-4-aminopyrrolidine-1,2-dicarboxylate hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2S,4S)-1-CBZ-4-aMino Pyrrolidine-2-carboxylic acid Methylester-HCl

There total 2 articles about (2S,4S)-1-CBZ-4-aMino Pyrrolidine-2-carboxylic acid Methylester-HCl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-benzyl 2-methyl (2S,4R)-4-(tert-butoxycarbonylamino)pyrrolidine-1,2-dicarboxylate (189215-90-5) → methyl (2S,4R)-4-amino-1-[benzyloxycarbonyl]pyrrolidine-2-carboxylate hydrochloride (1212395-57-7,489446-77-7)

Guidance literature:

With hydrogenchloride; In ethyl acetate;

DOI:10.1016/S0960-894X(02)00467-5

Reference yield:

4S-N4(t-boc)-N1-(benzyloxycarbonyl)-D-proline methylester → (2R,4S)-4-Amino-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester; hydrochloride (1212395-57-7,489446-77-7)

Guidance literature:

With hydrogenchloride; In ethyl acetate;

DOI:10.1016/S0960-894X(02)00467-5

upstream raw materials:

1-benzyl 2-methyl (2S,4R)-4-(tert-butoxycarbonylamino)pyrrolidine-1,2-dicarboxylate

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