N-benzylpyrimidin-5-amine

Base Information

Chemical Name:N-benzylpyrimidin-5-amine
CAS No.:104479-78-9
Molecular Formula:C11H11N3
Molecular Weight:185.22500
Hs Code.:2933599090
European Community (EC) Number:809-865-6
DSSTox Substance ID:DTXSID201320364
ChEMBL ID:CHEMBL1465808
Mol file:104479-78-9.mol

Synonyms:N-benzylpyrimidin-5-amine;104479-78-9;5-Pyrimidinamine, N-(phenylmethyl)-;N-benzyl-N-pyrimidin-5-ylamine;MLS001179429;CHEMBL1465808;N-Benzyl-N-(5-pyrimidinyl)amine;DTXSID201320364;HMS2826D10;5-pyrimidinamine,n-(phenylmethyl)-;AKOS006276429;SB56018;SMR000477230;CS-0447331;F18696;A896212

Suppliers and Price of N-benzylpyrimidin-5-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Benzylpyrimidin-5-amine
50mg
$ 90.00

SynQuest Laboratories
N-(Phenylmethyl)-5-pyrimidinamine
1 g
$ 432.00

SynQuest Laboratories
N-(Phenylmethyl)-5-pyrimidinamine
250 mg
$ 192.00

Crysdot
N-Benzylpyrimidin-5-amine 95+%
1g
$ 375.00

Chemenu
N-benzylpyrimidin-5-amine 95%
1g
$ 351.00

Apolloscientific
N-Benzylpyrimidin-5-amine
250mg
$ 174.00

Apolloscientific
N-Benzylpyrimidin-5-amine
1g
$ 392.00

Alichem
N-Benzylpyrimidin-5-amine
1g
$ 401.25

Total 9 raw suppliers

Chemical Property of N-benzylpyrimidin-5-amine

Chemical Property:

PSA：37.81000
LogP:2.16170
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:185.095297364
Heavy Atom Count:14
Complexity:149

Purity/Quality:

97% ^*data from raw suppliers

N-Benzylpyrimidin-5-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CNC2=CN=CN=C2

Technology Process of N-benzylpyrimidin-5-amine

There total 1 articles about N-benzylpyrimidin-5-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 4595-59-9
5-bromopyrimidine

: 100-46-9
benzylamine

: 104479-78-9
N-benzyl-5-aminopyrimidine

Guidance literature:: With cesium acetate; copper; In dimethyl sulfoxide; at 90 ℃; for 24h; Inert atmosphere;
DOI:10.1002/adsc.201000708

Reference yield:

: 191105-45-0
4-bromomethyl-2-(2-methylphenyl)benzoic acid methyl ester

: 104479-78-9
N-benzyl-5-aminopyrimidine

: 5-[(benzyl-pyrimidin-5-yl-amino)-methyl]-2'-methyl-biphenyl-2-carboxylic acid methyl ester

Guidance literature:: N-benzyl-5-aminopyrimidine; With n-butyllithium; In tetrahydrofuran; hexane; at -30 ℃; for 0.5h;

4-bromomethyl-2-(2-methylphenyl)benzoic acid methyl ester; In tetrahydrofuran; hexane; at -10 ℃; for 2h;
DOI:10.1021/jm9901935

Reference yield:

: 104479-78-9
N-benzyl-5-aminopyrimidine

: 5-[(benzyl-pyrimidin-5-yl-amino)-methyl]-2'-methyl-biphenyl-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -30 °C

1.2: tetrahydrofuran; hexane / 2 h / -10 °C

2.1: aq. NaOH / methanol / Heating

With sodium hydroxide; n-butyllithium; In tetrahydrofuran; methanol; hexane; 1.1: Metallation / 1.2: Substitution / 2.1: Hydrolysis;
DOI:10.1021/jm9901935