Technology Process of 25-Dihydrosaframycin A
There total 4 articles about 25-Dihydrosaframycin A which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
salcomine; oxygen;
In
acetonitrile;
at 20 ℃;
for 2.5h;
Inert atmosphere;
DOI:10.1021/jacs.8b07161
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 2-picoline borane complex / acetonitrile; water / 0.5 h / 20 °C / Inert atmosphere
2: lithium hydroxide monohydrate / tert-butyl alcohol; water / 8 h / 20 °C / Inert atmosphere
3: salcomine; oxygen / acetonitrile / 2.5 h / 20 °C / Inert atmosphere
With
salcomine; 2-picoline borane complex; lithium hydroxide monohydrate; oxygen;
In
water; acetonitrile; tert-butyl alcohol;
DOI:10.1021/jacs.8b07161
- Guidance literature:
-
Multi-step reaction with 2 steps
1: lithium hydroxide monohydrate / tert-butyl alcohol; water / 8 h / 20 °C / Inert atmosphere
2: salcomine; oxygen / acetonitrile / 2.5 h / 20 °C / Inert atmosphere
With
salcomine; lithium hydroxide monohydrate; oxygen;
In
water; acetonitrile; tert-butyl alcohol;
DOI:10.1021/jacs.8b07161
