XN974

Base Information

Chemical Name:XN974
CAS No.:189275-62-5
Molecular Formula:C₃₉H₃₈N₆O₃
Molecular Weight:638.769
Hs Code.:
Mol file:189275-62-5.mol

Synonyms:2H-1,3-Diazepin-2-one,hexahydro-5,6-dihydroxy-4,7-bis(phenylmethyl)-1,3-bis[[3-(1H-pyrazol-4-yl)phenyl]methyl]-,[4R-(4a,5a,6b,7b)]-

Suppliers and Price of XN974

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of XN974

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:918.1°Cat760mmHg
Flash Point:509°C
PSA：121.37000
Density:1.32g/cm³
LogP:5.72480

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of XN974

There total 4 articles about XN974 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₅₁H₆₄N₈O₁₁S₂

: 189275-62-5
(4R,5S,6S,7R)-4,7-Dibenzyl-5,6-dihydroxy-1,3-bis-[3-(1H-pyrazol-4-yl)-benzyl]-[1,3]diazepan-2-one

Guidance literature:: With hydrogenchloride; In methanol; for 16h; Yield given;
DOI:10.1021/jm9704199

Reference yield:

: 49617-83-6
m-Iodobenzyl bromide

: 189275-62-5
(4R,5S,6S,7R)-4,7-Dibenzyl-5,6-dihydroxy-1,3-bis-[3-(1H-pyrazol-4-yl)-benzyl]-[1,3]diazepan-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: NaH / dimethylformamide

2: Pd(PPh₃)4 / tetrahydrofuran / 18 h / 80 °C

3: 4M HCl in dioxane / methanol / 16 h

With hydrogenchloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydride; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm9704199

Reference yield:

: 153181-25-0
(4R,5S,6S,7R)-hexahydro-5,6-bis(2-methoxyethoxymethoxy)-4,7-bis(phenylmethyl)-2H-1,3-diazepin-2-one

: 189275-62-5
(4R,5S,6S,7R)-4,7-Dibenzyl-5,6-dihydroxy-1,3-bis-[3-(1H-pyrazol-4-yl)-benzyl]-[1,3]diazepan-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: NaH / dimethylformamide

2: Pd(PPh₃)4 / tetrahydrofuran / 18 h / 80 °C

3: 4M HCl in dioxane / methanol / 16 h

With hydrogenchloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydride; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm9704199