3-(2-bromoethyl)-6-methoxy-1H-indole

Base Information

Chemical Name:3-(2-bromoethyl)-6-methoxy-1H-indole
CAS No.:68104-24-5
Molecular Formula:C11H12BrNO
Molecular Weight:254.126
Hs Code.:
DSSTox Substance ID:DTXSID60471419
Nikkaji Number:J1.410.379A
Wikidata:Q82299922
Mol file:68104-24-5.mol

Synonyms:3-(2-bromoethyl)-6-methoxy-1H-indole;68104-24-5;1H-INDOLE,3-(2-BROMOETHYL)-6-METHOXY-;SCHEMBL3816723;DTXSID60471419;FJBFFCZCJJWVLC-UHFFFAOYSA-N;6-methoxy-3-(2-bromoethyl)indole;3-(2-Bromo-ethyl)-6-methoxy-1H-indole

Suppliers and Price of 3-(2-bromoethyl)-6-methoxy-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
1H-INDOLE,3-(2-BROMOETHYL)-6-METHOXY- 95
5g
$ 1633.00

American Custom Chemicals Corporation
1H-INDOLE,3-(2-BROMOETHYL)-6-METHOXY- 95.00%
5MG
$ 501.84

Total 4 raw suppliers

Chemical Property of 3-(2-bromoethyl)-6-methoxy-1H-indole

Chemical Property:

Boiling Point:381.2±27.0 °C(Predicted)
PKA:17.18±0.30(Predicted)
PSA：25.02000
Density:1.478±0.06 g/cm3(Predicted)
LogP:3.11390
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:253.01023
Heavy Atom Count:14
Complexity:188

Purity/Quality:

99% ^*data from raw suppliers

1H-INDOLE,3-(2-BROMOETHYL)-6-METHOXY- 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)C(=CN2)CCBr

Technology Process of 3-(2-bromoethyl)-6-methoxy-1H-indole

There total 1 articles about 3-(2-bromoethyl)-6-methoxy-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 41340-31-2
2-(6-methoxy-1H-indol-3-yl)ethan-1-ol

: 68104-24-5
6-methoxy-tryptophyl bromide

Guidance literature:: With carbon tetrabromide; triphenylphosphine; In acetonitrile; at 0 ℃;
DOI:10.1055/s-1986-31759

Reference yield: 69.0%

: 68104-24-5
6-methoxy-tryptophyl bromide

: 70617-03-7,96687-91-1
(4aR^*,5S^*,6S^*,7S^*,8aR^*)-6-methoxy-5-(methoxycarbonyl)-7-((3,4,5-trimethoxybenzoyl)oxy)perhydroisoquinoline

: 16625-53-9,96687-92-2,110013-47-3
2,3-seco-2,3-dihydroreserpine

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dimethyl sulfoxide; for 60h; Ambient temperature;
DOI:10.1021/ja00299a050

Reference yield:

: 68104-24-5
6-methoxy-tryptophyl bromide

: 75276-06-1
3,4,5-Trimethoxy-benzoic acid (1S,2R,3R,4aS,13bS,14aS)-1-formyl-2,11-dimethoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinolin-3-yl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 85 percent / K₂CO₃ / methanol / 25 h / Heating

2: 2.) NaBH₄

3: 53 percent

4: 62 percent / 0.3M KOH / methanol / 0.08 h / 25 °C

5: 65 percent / DCC, H₃PO₄ / dimethylsulfoxide

With potassium hydroxide; sodium tetrahydroborate; phosphoric acid; potassium carbonate; dicyclohexyl-carbodiimide; In methanol; dimethyl sulfoxide;
DOI:10.1021/ja00539a038