Vineridine

Base Information

Chemical Name:Vineridine
CAS No.:3489-06-3
Molecular Formula:C₂₂H₂₆N₂O₅
Molecular Weight:398.459
Hs Code.:
UNII:RAK4CV25QT
DSSTox Substance ID:DTXSID90956365
Nikkaji Number:J14.553J
Wikipedia:Vineridine
Wikidata:Q15088388
Mol file:3489-06-3.mol

Synonyms:Vineridine;Vineridin;Isocaboxine A;3489-06-3;7-Epivinerine;RAK4CV25QT;methyl (1S,4aS,5aR,6S,10aS)-6'-methoxy-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate;(3beta,7S,20alpha)-11-Methoxy-19alpha-methyl-2-oxoformosanan-16-carboxylic acid methyl ester;Formosanan-16-carboxylic acid, 11-methoxy-19-methyl-2-oxo-, methyl ester, (3-beta,7-alpha,19-alpha,20-alpha)-;UNII-RAK4CV25QT;DTXSID90956365;AKOS030495507;LS-69723;Q15088388;(1'S,3S,4a'S,5a'R,10a'S)-methyl 6-methoxy-1'-methyl-2-oxo-1',4a',5',5a',7',8',10',10a'-octahydrospiro[indoline-3,6'-pyrano[3,4-f]indolizine]-4'-carboxylate;FORMOSANAN-16-CARBOXYLIC ACID, 11-METHOXY-19-METHYL-2-OXO-, METHYL ESTER, (3.BETA.,7.ALPHA.,19.ALPHA.,20.ALPHA.)-;SPIRO(3H-INDOLE-3,6(4AH)-(1H)PYRANO(3,4-F)INDOLIZINE)-4-CARBOXYLIC ACID, 1,2,5,5A,7,8,10,10A-OCTAHYDRO-6-METHOXY-1-METHYL-2-OXO-, METHYL ESTER, (1S,3S,4AS,5AR,10AS)-;SPIRO(3H-INDOLE-3,6(4AH)-(1H)PYRANO(3,4-F)INDOLIZINE)-4-CARBOXYLIC ACID, 1,2,5,5A,7,8,10,10A-OCTAHYDRO-6-METHOXY-1-METHYL-2-OXO-, METHYL ESTER, (1S-(1.ALPHA.,4A.ALPHA.,5A.BETA.,6.ALPHA.,10A.ALPHA.))-

Suppliers and Price of Vineridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
VINERIDINE 95.00%
5MG
$ 504.14

Total 8 raw suppliers

Chemical Property of Vineridine

Chemical Property:

Vapor Pressure:2.23E-13mmHg at 25°C
Melting Point:l30-l88°C
Boiling Point:578.4°Cat760mmHg
Flash Point:303.6°C
PSA：80.59000
Density:1.33g/cm³
LogP:2.09410
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:398.18417193
Heavy Atom Count:29
Complexity:739

Purity/Quality:

98%min ^*data from raw suppliers

VINERIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C2CN3CCC4(C3CC2C(=CO1)C(=O)OC)C5=C(C=C(C=C5)OC)NC4=O
Isomeric SMILES:C[C@H]1[C@@H]2CN3CC[C@@]4([C@H]3C[C@@H]2C(=CO1)C(=O)OC)C5=C(C=C(C=C5)OC)NC4=O
Description The stem, stem bark, root and root bark of Cabucala fasciculata have been found to contain a number of new alkaloids which have been chiefly investigated by Titeux and his colleagues. This base is separated from the accompanying alkaloids by column chromatography. It forms colourless crystals which melt over a very wide range of temperature. Isocarboxine A has a specific rotation of [α]D + 31.7° (CHC13).

Technology Process of Vineridine

There total 4 articles about Vineridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13281-23-7
7-acetoxy-11-methoxy-19α-methyl-(7ξ,20α)-7H-18-oxa-yohimb-16-ene-16-carboxylic acid methyl ester

: 3382-38-5,3489-06-3,13483-85-7,19775-58-7,53851-13-1,61665-08-5,62358-35-4,62358-36-5
reserpinine oxindole

Guidance literature:: With acetic acid; In methanol; water;
DOI:10.1007/BF00564092

Reference yield:

: 482-96-2
reserpinine

: 3382-38-5,3489-06-3,13483-85-7,19775-58-7,53851-13-1,61665-08-5,62358-35-4,62358-36-5
reserpinine oxindole

Guidance literature:: Multi-step reaction with 2 steps

1: CH₂Cl₂

2: AcOH / methanol; H₂O

With acetic acid; In methanol; dichloromethane; water;
DOI:10.1007/BF00564092