DL-Methylephedrine hydrochloride

Base Information

• Chemical Name: DL-Methylephedrine hydrochloride
• CAS No.: 942-46-1
• Molecular Formula: C11H17NO.ClH
• Molecular Weight: 215.72000
• European Community (EC) Number: 242-557-4
• DSSTox Substance ID: DTXSID40916196
• Wikidata: Q27148434
• NCI Thesaurus Code: C77293
• Mol file: 942-46-1.mol

Synonyms:DL-Methylephedrine hydrochloride;18760-80-0;rac-Methyl Ephedrine Hydrochloride;C11H17NO.ClH;L-N-Methylephedrine hydrochloride;dl-N-Methylephedrine hydrochloride;EINECS 242-557-4;Methy-F (TN);(R*,S*)-(+-)-alpha-[1-(dimethylamino)ethyl]benzyl alcohol hydrochloride;CHEBI:79398;DTXSID40916196;Benzenemethanol, .alpha.-[1-(dimethylamino)ethyl]-, hydrochloride, (R*,S*)-(.+-.)-;Benzenemethanol, .alpha.-[1-(dimethylamino)ethyl]-, hydrochloride, (R*,S*)-(.+.)-;Benzenemethanol, .alpha.-[1-(dimethylamino)ethyl]-, hydrochloride, [R-(R*,S*)]-;Benzenemethanol, alpha-(1-(dimethylamino)ethyl)-, hydrochloride, (R*,S*)-(+-)- (9CI);Benzenemethanol, alpha-(1-(dimethylamino)ethyl)-, hydrochloride,(R*,S*)-(+)-;Benzyl alcohol, .alpha.-[1-(dimethylamino)ethyl]-, hydrochloride, erythro-(.+.)-;942-46-1;(+/-)-N-Methylephedrine Hydrochloride;dl-Methylephedrine hydrochloride (JP17);D02109;J-012074;Q27148434;2-(Dimethylamino)-1-phenylpropan-1-ol--hydrogen chloride (1/1)

Chemical Property of DL-Methylephedrine hydrochloride

Chemical Property:

• PSA: 23.47000
• LogP: 2.47210
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 215.1076919
• Heavy Atom Count: 14
• Complexity: 141

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(C1=CC=CC=C1)O)N(C)C.Cl

Technology Process of DL-Methylephedrine hydrochloride

There total 2 articles about DL-Methylephedrine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(-)-N-methylephedrine (552-79-4) → (1R,2S)(-)-methylephedrinium chloride (942-46-1,4125-59-1,18760-80-0,30891-72-6,38455-90-2,54114-10-2,65326-26-3,69792-63-8)

Guidance literature:

With hydrogenchloride; In water; at 50 ℃; for 0.5h;

DOI:10.1021/cg200030s

Reference yield:

(+/-)-N-methylephedrine (1201-56-5) → (+/-)-methylephedrinium chloride (942-46-1,4125-59-1,18760-80-0,30891-72-6,38455-90-2,54114-10-2,65326-26-3,69792-63-8)

Guidance literature:

With hydrogenchloride; In water; at 50 ℃; for 0.5h;

DOI:10.1021/cg200030s

Reference yield:

C70H72N16O24S4(4-)*4Na(1+) + (1R,2S)(-)-methylephedrinium chloride (942-46-1,4125-59-1,18760-80-0,30891-72-6,38455-90-2,54114-10-2,65326-26-3,69792-63-8) → C70H72N16O24S4(4-)*4Na(1+)*C11H17NO*ClH

Guidance literature:

In water-d2; at 25 ℃;

DOI:10.1039/d1ob00345c

upstream raw materials:

(-)-N-methylephedrine

(+/-)-N-methylephedrine