4,6-Dimethoxy-pyrazolo[3,4-d]pyrimidine

Base Information

Chemical Name:4,6-Dimethoxy-pyrazolo[3,4-d]pyrimidine
CAS No.:98277-30-6
Molecular Formula:C7H8N4O2
Molecular Weight:180.166
Hs Code.:2933990090
Mol file:98277-30-6.mol

Synonyms:4,6-DIMETHOXY-PYRAZOLO[3,4-D]PYRIMIDINE;4,6-dimethoxy-1H-pyrazolo[3,4-d]pyrimidine

Suppliers and Price of 4,6-Dimethoxy-pyrazolo[3,4-d]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4,6-Dimethoxy-1H-pyrazolo[3,4-d]pyrimidine
500mg
$ 420.00

Crysdot
4,6-Dimethoxy-1H-pyrazolo[3,4-d]pyrimidine 97%
1g
$ 761.00

Chemenu
4,6-Dimethoxy-1H-pyrazolo[3,4-d]pyrimidine 97%
1g
$ 719.00

American Custom Chemicals Corporation
4,6-DIMETHOXY-PYRAZOLO(3,4-D)PYRIMIDINE 95.00%
5G
$ 3811.50

Total 8 raw suppliers

Chemical Property of 4,6-Dimethoxy-pyrazolo[3,4-d]pyrimidine

Chemical Property:

PSA：72.92000
LogP:0.37010
Solubility.:Methanol

Purity/Quality:

98% ^*data from raw suppliers

4,6-Dimethoxy-1H-pyrazolo[3,4-d]pyrimidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 4,6-Dimethoxy-1H-pyrazolo[3,4-d]pyrimidine is an intermediate in the synthesis of 4,6-Dihydroxypyrazolo[3,4-d]pyrimidine (D454550). 4,6-Dihydroxypyrazolo[3,4-d]pyrimidine is a major metabolite of Allopurinol (A547300). It is a xanthine oxidase inhibitor.

Technology Process of 4,6-Dimethoxy-pyrazolo[3,4-d]pyrimidine

There total 4 articles about 4,6-Dimethoxy-pyrazolo[3,4-d]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 134221-52-6
4-chloro-2,6-dimethoxypyrimidine-5-carboxaldehyde

: 98277-30-6
4,6-dimethoxy-1H-pyrazolo[3,4-d]pyrimidine

Guidance literature:: With hydrazine hydrate; In ethanol; for 0.5h; Heating;
DOI:10.1021/ol061295+

Reference yield:

: 42362-16-3
5-bromo-4-chloro-2,6-dimethoxypyrimidine

: 98277-30-6
4,6-dimethoxy-1H-pyrazolo[3,4-d]pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1.1: i-PrMgCl*LiCl / tetrahydrofuran / 0.25 h / 20 °C

1.2: 82 percent / tetrahydrofuran / 4 h / -35 °C

2.1: 91 percent / hydrazine monohydrate / ethanol / 0.5 h / Heating

With TurboGrignard; hydrazine hydrate; In tetrahydrofuran; ethanol;
DOI:10.1021/ol061295+

Reference yield:

: 2465-59-0
oxypurinol

: 98277-30-6
4,6-dimethoxy-1H-pyrazolo[3,4-d]pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-diethyl-aniline; POCl₃

2: methanol

With methanol; N,N-diethylaniline; trichlorophosphate;