6-Ethynyl-1H-imidazo[4,5-b]pyridine

Base Information

Chemical Name:6-Ethynyl-1H-imidazo[4,5-b]pyridine
CAS No.:351325-04-7
Molecular Formula:C8H5N3
Molecular Weight:143.14500
Hs Code.:
DSSTox Substance ID:DTXSID10592466
Mol file:351325-04-7.mol

Synonyms:6-Ethynyl-1H-imidazo[4,5-b]pyridine;351325-04-7;6-ethynyl-3H-imidazo[4,5-b]pyridine;1H-Imidazo[4,5-b]pyridine,6-ethynyl-(9CI);SCHEMBL503820;DTXSID10592466;BPA32504;AKOS006357475;AT36249;DB-091117

Suppliers and Price of 6-Ethynyl-1H-imidazo[4,5-b]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
6-ethynyl-1H-imidazo[4,5-b]pyridine 95%
1g
$ 729.00

American Custom Chemicals Corporation
6-ETHYNYL-1H-IMIDAZO[4,5-B]PYRIDINE 95.00%
5MG
$ 498.66

Alichem
6-Ethynyl-1H-imidazo[4,5-b]pyridine
5g
$ 4261.20

Alichem
6-Ethynyl-1H-imidazo[4,5-b]pyridine
1g
$ 1591.92

Total 7 raw suppliers

Chemical Property of 6-Ethynyl-1H-imidazo[4,5-b]pyridine

Chemical Property:

PSA：41.57000
LogP:0.93920
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:143.048347172
Heavy Atom Count:11
Complexity:193

Purity/Quality:

99% ^*data from raw suppliers

6-ethynyl-1H-imidazo[4,5-b]pyridine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C#CC1=CC2=C(N=C1)N=CN2

Technology Process of 6-Ethynyl-1H-imidazo[4,5-b]pyridine

There total 2 articles about 6-Ethynyl-1H-imidazo[4,5-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 6-(2-trimethylsilylethynyl)-imidazo[4,5-b]pyridine

: 351325-04-7
6-ethynylimidazo[4,5-b]pyridine

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 0.25h;

Reference yield:

: 28279-49-4
6-bromo-1H-imidazo[4,5-b]pyridine

: 351325-04-7
6-ethynylimidazo[4,5-b]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; copper(l) iodide / N,N-dimethyl-formamide / 1 h / 20 °C / Inert atmosphere

2: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.25 h / 20 °C

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetrabutyl ammonium fluoride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; N,N-dimethyl-formamide;