1-(2-PHENOXYETHYL)-PIPERAZINE

Base Information

• Chemical Name: 1-(2-PHENOXYETHYL)-PIPERAZINE
• CAS No.: 13484-37-2
• Molecular Formula: C12H18N2O
• Molecular Weight: 206.288
• Hs Code.: 29339900
• Mol file: 13484-37-2.mol

Synonyms:1-[2-(Phenoxy)-ethyl]piperazine;1-(2-phenoxyethyl)piperazine;1-(2-phenoxyethyl)-2,3,5,6-tetrahydropyrazine;

Chemical Property of 1-(2-PHENOXYETHYL)-PIPERAZINE

Chemical Property:

• Vapor Pressure: 0.000124mmHg at 25°C
• Boiling Point: 334.9 °C at 760 mmHg
• Flash Point: 156.4 °C
• PSA: 24.50000
• Density: 1.033 g/cm³
• LogP: 1.23730

Purity/Quality:

97% ^*data from raw suppliers

1-(2-Phenoxyethyl)piperazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,Xn
• Statements: 22-20/21/22
• Safety Statements: 23-24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(2-PHENOXYETHYL)-PIPERAZINE

There total 9 articles about 1-(2-PHENOXYETHYL)-PIPERAZINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

4-(2-phenoxyethyl)piperazine-1-carboxylic acid tert-butylester → 1-[2-phenoxyethyl]piperazine (13484-37-2)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1016/j.ejmech.2018.01.092

Reference yield: 81.0%

1-ethoxycarbonyl-4-(2-phenoxyethyl)piperazine hydrochloride (88701-82-0) → 1-[2-phenoxyethyl]piperazine (13484-37-2)

Guidance literature:

With potassium hydroxide; In ethanol;

DOI:10.1135/cccc19832395

Reference yield: 76.0%

piperazine (110-85-0) + phenoxyethyl bromide (589-10-6) → 1-[2-phenoxyethyl]piperazine (13484-37-2)

Guidance literature:

In toluene; at 85 ℃; for 2h;

DOI:10.1071/CH08307

upstream raw materials:

piperazine

2-chloroethoxybenzene

1-ethoxycarbonyl-4-(2-phenoxyethyl)piperazine hydrochloride

1-benzyl-4-(2-phenoxy-ethyl)-piperazine

Downstream raw materials:

1-{2-Oxo-2-[4-(2-phenoxy-ethyl)-piperazin-1-yl]-ethyl}-pyrrolidin-2-one

1-(2-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-(2-phenoxy-ethyl)-piperazine

1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-(2-phenoxy-ethyl)-piperazine

4-chloro-5-<4-(2-phenoxyethyl)-1-piperazinyl>-3(2H)-pyridazinone

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