(1S,5R)-1β,2-Dimethyl-2α-(4-methylphenyl)bicyclo[3.1.0]hexane

Base Information

Chemical Name:(1S,5R)-1β,2-Dimethyl-2α-(4-methylphenyl)bicyclo[3.1.0]hexane
CAS No.:103439-82-3
Molecular Formula:C₁₅H₂₀
Molecular Weight:200.324
Hs Code.:
Mol file:103439-82-3.mol

Synonyms:Bicyclo[3.1.0]hexane,1,2-dimethyl-2-(4-methylphenyl)-, [1S-(1a,2b,5a)]-; Cyclolaurene

Suppliers and Price of (1S,5R)-1β,2-Dimethyl-2α-(4-methylphenyl)bicyclo[3.1.0]hexane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (1S,5R)-1β,2-Dimethyl-2α-(4-methylphenyl)bicyclo[3.1.0]hexane

Chemical Property:

PSA：0.00000
LogP:4.07270

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1S,5R)-1β,2-Dimethyl-2α-(4-methylphenyl)bicyclo[3.1.0]hexane

There total 15 articles about (1S,5R)-1β,2-Dimethyl-2α-(4-methylphenyl)bicyclo[3.1.0]hexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 141972-48-7
(E)-2-Methyl-3-p-tolyl-but-2-en-1-ol

: 103439-82-3,142035-91-4,142035-92-5
Cyclolaurene

Guidance literature:: Multi-step reaction with 8 steps

1: 68 percent / propionic acid / toluene / 36 h / 160 °C

2: 86 percent / 10percent aq. NaOH / methanol / 8 h / Heating

3: (COCl)2 / benzene / 5 h / Ambient temperature

4: diethyl ether / 3 h / Ambient temperature

5: CuSO₄ / cyclohexane / 5 h / Heating

6: 22.5 percent / NaBH₄ / methanol / 10 h / Ambient temperature

7: 94 percent / pyridinium chlorochromate, NaOAc / CH₂Cl₂ / 3 h / Ambient temperature

8: 1) 99percent N₂H₄*H₂O, 2) Na / 1) ethanediol, digol, 184 deg C, 90 min, 2) digol, 4 h, reflux

With sodium hydroxide; sodium tetrahydroborate; oxalyl dichloride; sodium acetate; sodium; hydrazine hydrate; propionic acid; pyridinium chlorochromate; copper(II) sulfate; In methanol; diethyl ether; dichloromethane; cyclohexane; toluene; benzene;
DOI:10.1016/0040-4020(92)85016-8

Reference yield:

: 141972-48-7
(E)-2-Methyl-3-p-tolyl-but-2-en-1-ol

: 103439-82-3,142035-91-4,142035-92-5
Epicyclolaurene

Guidance literature:: Multi-step reaction with 8 steps

1: 68 percent / propionic acid / toluene / 36 h / 160 °C

2: 86 percent / 10percent aq. NaOH / methanol / 8 h / Heating

3: (COCl)2 / benzene / 5 h / Ambient temperature

4: diethyl ether / 3 h / Ambient temperature

5: CuSO₄ / cyclohexane / 5 h / Heating

6: 46 percent / NaBH₄ / methanol / 10 h / Ambient temperature

7: 95 percent / pyridinium chlorochromate, NaOAc / CH₂Cl₂ / 3 h / Ambient temperature

8: 1) 99percent N₂H₄*H₂O, 2) Na / 1) ethanediol, digol, 184 deg C, 90 min, 2) digol, 4 h, reflux

With sodium hydroxide; sodium tetrahydroborate; oxalyl dichloride; sodium acetate; sodium; hydrazine hydrate; propionic acid; pyridinium chlorochromate; copper(II) sulfate; In methanol; diethyl ether; dichloromethane; cyclohexane; toluene; benzene;
DOI:10.1016/0040-4020(92)85016-8

Reference yield:

: 3,4-Dimethyl-3-p-tolyl-pent-4-enoyl chloride

: 103439-82-3,142035-91-4,142035-92-5
Cyclolaurene

Guidance literature:: Multi-step reaction with 5 steps

1: diethyl ether / 3 h / Ambient temperature

2: CuSO₄ / cyclohexane / 5 h / Heating

3: 22.5 percent / NaBH₄ / methanol / 10 h / Ambient temperature

4: 94 percent / pyridinium chlorochromate, NaOAc / CH₂Cl₂ / 3 h / Ambient temperature

5: 1) 99percent N₂H₄*H₂O, 2) Na / 1) ethanediol, digol, 184 deg C, 90 min, 2) digol, 4 h, reflux

With sodium tetrahydroborate; sodium acetate; sodium; hydrazine hydrate; pyridinium chlorochromate; copper(II) sulfate; In methanol; diethyl ether; dichloromethane; cyclohexane;
DOI:10.1016/0040-4020(92)85016-8