2-[[(2R,4R)-2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2lambda5-oxazaphosphinan-4-yl]sulfanyl]ethanesulfonic acid

Base Information

Chemical Name:2-[[(2R,4R)-2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2lambda5-oxazaphosphinan-4-yl]sulfanyl]ethanesulfonic acid
CAS No.:88859-04-5
Molecular Formula:C₉H₁₉Cl₂N₂O₅PS₂
Molecular Weight:401.272
Hs Code.:
Mol file:88859-04-5.mol

Synonyms:SCHEMBL25460

Suppliers and Price of 2-[[(2R,4R)-2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2lambda5-oxazaphosphinan-4-yl]sulfanyl]ethanesulfonic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
MAFOSFAMIDE 95.00%
5MG
$ 505.73

American Custom Chemicals Corporation
MAFOSFAMIDE 95.00%
1MG
$ 367.50

Total 31 raw suppliers

Chemical Property of 2-[[(2R,4R)-2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2lambda5-oxazaphosphinan-4-yl]sulfanyl]ethanesulfonic acid

Chemical Property:

Refractive Index:1.573
PSA：139.43000
Density:1.54 g/cm³
LogP:3.24070
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:9
Exact Mass:399.9850064
Heavy Atom Count:21
Complexity:456

Purity/Quality:

99%, ^*data from raw suppliers

MAFOSFAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COP(=O)(NC1SCCS(=O)(=O)O)N(CCCl)CCCl
Isomeric SMILES:C1CO[P@](=O)(N[C@@H]1SCCS(=O)(=O)O)N(CCCl)CCCl

Technology Process of 2-[[(2R,4R)-2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2lambda5-oxazaphosphinan-4-yl]sulfanyl]ethanesulfonic acid

There total 4 articles about 2-[[(2R,4R)-2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2lambda5-oxazaphosphinan-4-yl]sulfanyl]ethanesulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 88859-04-5
mafosfamide

Guidance literature:

Reference yield:

: 84210-72-0,88859-04-5
cis-Mosfosfamide

: 35144-64-0
aldophosphamide

: 88685-78-3
aldophosphamide hydrate

: 61903-29-5,88852-77-1,40277-05-2,61903-30-8,88852-78-2
cis-4-hydroxycyclophosphamide

: 61903-30-8,88852-78-2,40277-05-2,61903-29-5,88852-77-1
trans-4-hydroxycyclophosphamide

: 105639-84-7
C₉H₂₁Cl₂N₂O₆PS₂

: 92745-18-1,88859-04-5
2-{(2S,4S)-2-[Bis-(2-chloro-ethyl)-amino]-2-oxo-2λ⁵-[1,3,2]oxazaphosphinan-4-ylsulfanyl}-ethanesulfonic acid

Guidance literature:: With acetate bufer; In water; at 37 ℃; Rate constant; Mechanism; var. buffer conc., var. pH, var. ionic strength;
DOI:10.1021/jm00385a023