8-Chloroimidazo[1,5-A]pyrazine

Base Information

Chemical Name:8-Chloroimidazo[1,5-A]pyrazine
CAS No.:56468-23-6
Molecular Formula:C6H4ClN3
Molecular Weight:153.571
Hs Code.:2933990090
European Community (EC) Number:838-461-2
DSSTox Substance ID:DTXSID20481973
Wikidata:Q82317787
Mol file:56468-23-6.mol

Synonyms:8-CHLOROIMIDAZO[1,5-A]PYRAZINE;56468-23-6;8-Chloro-imidazo[1,5-a]pyrazine;MFCD20040069;SCHEMBL1129049;DTXSID20481973;AFQLYSHHYYOVDJ-UHFFFAOYSA-N;AKOS021948362;AS-41593;SY147472;CS-0097636;EN300-114090;A869936;Z1263714580

Suppliers and Price of 8-Chloroimidazo[1,5-A]pyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
8-Chloroimidazo[1,5-a]pyrazine
50mg
$ 175.00

TRC
8-Chloroimidazo[1,5-a]pyrazine
100mg
$ 285.00

TRC
8-Chloroimidazo[1,5-a]pyrazine
10mg
$ 45.00

SynQuest Laboratories
8-Chloroimidazo[1,5-a]pyrazine
250 mg
$ 500.00

Crysdot
8-Chloroimidazo[1,5-a]pyrazine 95+%
250mg
$ 345.00

Chemenu
8-Chloroimidazo[1,5-a]pyrazine 95+%
250mg
$ 435.00

Chemenu
8-Chloroimidazo[1,5-a]pyrazine 95+%
100mg
$ 272.00

Chemenu
8-Chloroimidazo[1,5-a]pyrazine 95+%
1g
$ 1078.00

Ambeed
8-Chloroimidazo[1,5-a]pyrazine 95+%
250mg
$ 663.00

Ambeed
8-Chloroimidazo[1,5-a]pyrazine 95+%
1g
$ 663.00

Total 15 raw suppliers

Chemical Property of 8-Chloroimidazo[1,5-A]pyrazine

Chemical Property:

Melting Point:105-106 °C(Solv: ethyl ether (60-29-7); hexane (110-54-3))
PKA:3.45±0.30(Predicted)
PSA：30.19000
Density:1.51±0.1 g/cm3(Predicted)
LogP:1.38270
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:153.0093748
Heavy Atom Count:10
Complexity:130

Purity/Quality:

97% ^*data from raw suppliers

8-Chloroimidazo[1,5-a]pyrazine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN2C=NC=C2C(=N1)Cl

Technology Process of 8-Chloroimidazo[1,5-A]pyrazine

There total 3 articles about 8-Chloroimidazo[1,5-A]pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 940307-81-3
N-((3-chloropyrazin-2-yl)methyl)carboxamide

: 56468-23-6
8-chloro-imidazo[1,5-a]pyrazine

Guidance literature:: N-((3-chloropyrazin-2-yl)methyl)carboxamide; With trichlorophosphate; In acetonitrile; at 20 ℃; for 0.0833333h;

In N,N-dimethyl-formamide; acetonitrile; at 75 ℃;

With ammonia; In isopropyl alcohol; at 0 ℃; pH=9;

Reference yield:

: 771581-15-8
(3-chloro-pyrazin-2-yl)-methylamine

: 56468-23-6
8-chloro-imidazo[1,5-a]pyrazine

Guidance literature:: Multi-step reaction with 2 steps

1: 12 h / 110 °C / Inert atmosphere

2: trichlorophosphate / N,N-dimethyl-formamide; acetonitrile / 4 h / 0 - 20 °C

With trichlorophosphate; In N,N-dimethyl-formamide; acetonitrile;