1-(1-Benzothiophen-4-yl)piperazine hydrochloride

Base Information

• Chemical Name: 1-(1-Benzothiophen-4-yl)piperazine hydrochloride
• CAS No.: 913614-18-3
• Molecular Formula: C12H15ClN2S
• Molecular Weight: 254.77900
• Hs Code.: 2934999090
• Mol file: 913614-18-3.mol

Synonyms:

Chemical Property of 1-(1-Benzothiophen-4-yl)piperazine hydrochloride

Chemical Property:

• Melting Point: >250°C (dec.)
• PSA: 43.51000
• LogP: 3.50670
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility.: DMSO (Slightly, Heated), Methanol (Very Slightly)

Purity/Quality:

99%, ^*data from raw suppliers

1-Benzo[b]thien-4-yl-piperazineMonohydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 4-Piperazinylbenzothiophene hydrochloride is the raw material for preparing piperazine-substituted benzothiophene, which can be used for the treatment and prevention of mental diseases including central nervous system diseases.

Technology Process of 1-(1-Benzothiophen-4-yl)piperazine hydrochloride

There total 1 articles about 1-(1-Benzothiophen-4-yl)piperazine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

benzo[B]thiophen-4-ylamine (17402-83-4) + bis-(2-chloroethyl)amine hydrochloride (821-48-7) → 1-(benzo[b]thiophen-4-yl)piperazine hydrochloride (1677681-05-8,913614-18-3)

Guidance literature:

With toluene-4-sulfonamide; In 5,5-dimethyl-1,3-cyclohexadiene; at 120 - 150 ℃; for 16h;

Reference yield: 92.4%

1-(benzo[b]thiophen-4-yl)piperazine hydrochloride (1677681-05-8,913614-18-3) + 7-(4-chlorobutoxy)-1H-quinazolin-2-one → 7-[4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one hydrochloride

Guidance literature:

1-(benzo[b]thiophen-4-yl)piperazine hydrochloride; With potassium carbonate; potassium iodide; In dimethyl sulfoxide; at 70 ℃;

7-(4-chlorobutoxy)-1H-quinazolin-2-one; In dimethyl sulfoxide; at 80 ℃; for 12h; Solvent; Reagent/catalyst;

Reference yield:

1-(benzo[b]thiophen-4-yl)piperazine hydrochloride (1677681-05-8,913614-18-3) + 7-(4-bromobutoxy-1,1,2,2,3,3,4,4-d8)-1H-quinolin-2-one (1427053-44-8) → 7-[4-(4-benzo[b]thiophen-4-ylpiperazin-1-yl)butoxy-1,1,2,2,3,3,4,4-d8]-1H-quinolin-2-one (1427049-19-1)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 6h;

upstream raw materials:

benzo[B]thiophen-4-ylamine

bis-(2-chloroethyl)amine hydrochloride

Downstream raw materials:

7-[4-(4-benzo[b]thiophen-4-ylpiperazin-1-yl)butoxy-1,1,2,2,3,3,4,4-d₈]-1H-quinolin-2-one

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 913614-18-3 1-(1-Benzothiophen-4-yl)piperazine hydrochloride

Send

Send

Metric Ton KG G Pound L ML

Send

Send