Bromofosfamide

Base Information

Chemical Name:Bromofosfamide
CAS No.:104149-14-6
Molecular Formula:C₇H₁₅BrClN₂O₂P
Molecular Weight:305.539
Hs Code.:2934999090
UNII:J92CV4ATFN
DSSTox Substance ID:DTXSID70908827
Nikkaji Number:J531.562J
Wikidata:Q27281361
ChEMBL ID:CHEMBL78097
Mol file:104149-14-6.mol

Synonyms:bromofosfamide;CBM-11;N,N'-bis(2-bromoethyl)phosphorodiamidic acid;N,N'-bis(BrEt)isophosphoramide;N,N'-bis-(2-bromoethyl)phosphorodiamidic acid

Suppliers and Price of Bromofosfamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
BROMOFOSFAMIDE 95.00%
5MG
$ 503.42

Total 2 raw suppliers

Chemical Property of Bromofosfamide

Chemical Property:

Vapor Pressure:4.62E-05mmHg at 25°C
Boiling Point:349.7°Cat760mmHg
Flash Point:165.3°C
PSA：51.38000
Density:1.54g/cm³
LogP:2.36890
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:303.97430
Heavy Atom Count:14
Complexity:220

Purity/Quality:

More than 98% ^*data from raw suppliers

BROMOFOSFAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(P(=O)(OC1)NCCBr)CCCl

Technology Process of Bromofosfamide

There total 3 articles about Bromofosfamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 29102-47-4
2-aziridino-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin 2-oxide

: 104149-14-6,146452-36-0
N-(2-bromoethyl)-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

Guidance literature:: With hydrogen bromide; In chloroform; for 0.25h; Ambient temperature;
DOI:10.1021/jm00396a036

Reference yield:

: 3778-73-2,84711-20-6
ilfosfamide

: 104149-14-6,146452-36-0
N-(2-bromoethyl)-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / tetrahydrofuran

2: 77 percent / aq. HBr / CHCl₃ / 0.25 h / Ambient temperature

With hydrogen bromide; sodium hydride; In tetrahydrofuran; chloroform;
DOI:10.1021/jm00396a036