7-Nitro-1H-indazol-6-aMine

Base Information

• Chemical Name: 7-Nitro-1H-indazol-6-aMine
• CAS No.: 74728-64-6
• Molecular Formula: C7H6N4O2
• Molecular Weight: 178.14800
• Hs Code.: 2933990090
• Mol file: 74728-64-6.mol

Synonyms:

Chemical Property of 7-Nitro-1H-indazol-6-aMine

Chemical Property:

• PSA: 100.52000
• LogP: 2.15770
• Storage Temp.: 2-8°C

Purity/Quality:

≥99% ^*data from raw suppliers

7-nitro-1H-indazol-6-amine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7-Nitro-1H-indazol-6-aMine

There total 3 articles about 7-Nitro-1H-indazol-6-aMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

7-Nitroindazole (2942-42-9) → 4-amino-7-nitro-1H-indazole (918961-25-8) + amino-6 nitro-7 indazole (74728-64-6) + 8H-[1,2,5]oxadiazolo[3,4-g]indazole

Guidance literature:

7-Nitroindazole; With 4-amino-1,2,4-triazole; In dimethyl sulfoxide; at 60 ℃;

With potassium tert-butylate; In dimethyl sulfoxide; at 60 ℃; for 2h; regioselective reaction;

DOI:10.1055/a-1672-7285

Reference yield:

N-(7-nitro-1(2)H-indazol-6-yl)-acetamide (99512-76-2) → amino-6 nitro-7 indazole (74728-64-6)

Guidance literature:

With hydrogenchloride;

Reference yield:

6-amino-1H-indazole (6967-12-0) → amino-6 nitro-7 indazole (74728-64-6)

Guidance literature:

Multi-step reaction with 2 steps

1: beim aufeinanderfolgenden Behandeln mit Acetanhydrid und Essigsaeure und mit HNO₃

2: aqueous HCl

With hydrogenchloride;

upstream raw materials:

N-(7-nitro-1⁽²⁾H-indazol-6-yl)-acetamide

6-amino-1H-indazole

7-Nitroindazole

Refernces