4-ETHYLPHENYLACETONITRILE

Base Information

• Chemical Name: 4-ETHYLPHENYLACETONITRILE
• CAS No.: 51632-28-1
• Molecular Formula: C10H11N
• Molecular Weight: 145.204
• Hs Code.: 2926909090
• Mol file: 51632-28-1.mol

Synonyms:Acetonitrile,(p-ethylphenyl)- (6CI,7CI);(4-Ethylphenyl)acetonitrile;4-Ethylbenzeneacetonitrile;4-Ethylbenzyl cyanide;

Chemical Property of 4-ETHYLPHENYLACETONITRILE

Chemical Property:

• Vapor Pressure: 0.0189mmHg at 25°C
• Refractive Index: 1.5164
• Boiling Point: 252.8 °C at 760 mmHg
• Flash Point: 116.1 °C
• PSA: 23.79000
• Density: 0.978g/cm³
• LogP: 2.31508
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

4-Ethylphenylacetonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 20/21/22
• Safety Statements: 23-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-ETHYLPHENYLACETONITRILE

There total 10 articles about 4-ETHYLPHENYLACETONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.2%

2,3,4-trimethoxybenzaldehyde (2103-57-3) → α-cyano-4-ethyl-2',3',4'-trimethoxystilbene + (4-ethyl-phenyl)-acetonitrile (51632-28-1)

Guidance literature:

Reference yield: 72.4%

sodium cyanide (143-33-9,25596-52-5) + 4-ethylbenzylchloride (1467-05-6) → (4-ethyl-phenyl)-acetonitrile (51632-28-1)

Guidance literature:

In dimethyl sulfoxide;

DOI:10.1135/cccc19840122

Reference yield: 60.0%

4-ethylbenzyl bromide (57825-30-6) + sodium cyanide (143-33-9,25596-52-5) → (4-ethyl-phenyl)-acetonitrile (51632-28-1)

Guidance literature:

In ethanol; water; Heating;

DOI:10.1021/ol0713990

upstream raw materials:

sodium cyanide

4-ethylbenzylchloride

4-ethylbenzyl bromide

4-ethylbenzyl alcohol

Downstream raw materials:

2-(4-ethyl-phenyl)-3c-[2]furyl-acrylonitrile

(4-ethyl-phenyl)-acetic acid

4-ethylphenylethylamine

2-(4-ethyl-phenyl)-3c-(4-dimethylamino-phenyl)-acrylonitrile

Refernces

• 1、 Law, Ho,Dukat, Malgorzata,Teitler, Milt,Lee, David K. H.,Mazzocco, Lucia,Kamboj, Raj,Rampersad, Vik,Prisinzano, Thomas,Glennon, Richard A.. "Benzylimidazolines as h5-HT(1B/1D) serotonin receptor ligands: A structure-affinity investigation". . p. 2243 - 2251. Retrieved 2007/10/03.
• 2、 -. "Stilbene derivative and stilbene analog derivative, and use thereof". . . Retrieved 2008/06/13.