2-(Trifluoromethyl)pyrimidine-4-carboxamide

Base Information

Chemical Name:2-(Trifluoromethyl)pyrimidine-4-carboxamide
CAS No.:914348-10-0
Molecular Formula:C6H4F3N3O
Molecular Weight:191.11100
Hs Code.:2933599590
European Community (EC) Number:689-919-1
DSSTox Substance ID:DTXSID80590277
Wikidata:Q82484009
Mol file:914348-10-0.mol

Synonyms:2-(Trifluoromethyl)pyrimidine-4-carboxamide;914348-10-0;SCHEMBL2791548;DTXSID80590277;LBNILUATVOCQRF-UHFFFAOYSA-N;MFCD05662689;AKOS025117085;SB56304;AS-47715;DB-292042;F15721;A843917

Suppliers and Price of 2-(Trifluoromethyl)pyrimidine-4-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(Trifluoromethyl)pyrimidine-4-carboxamide
50mg
$ 45.00

SynQuest Laboratories
2-(Trifluoromethyl)pyrimidine-4-carboxamide
1 g
$ 269.00

Crysdot
2-(Trifluoromethyl)pyrimidine-4-carboxamide 97%
1g
$ 321.00

Apolloscientific
2-(Trifluoromethyl)pyrimidine-4-carboxamide
1g
$ 168.00

American Custom Chemicals Corporation
2-(TRIFLUOROMETHYL)PYRIMIDINE-4-CARBOXAMIDE 95.00%
250MG
$ 197.40

American Custom Chemicals Corporation
2-(TRIFLUOROMETHYL)PYRIMIDINE-4-CARBOXAMIDE 95.00%
5G
$ 1322.48

American Custom Chemicals Corporation
2-(TRIFLUOROMETHYL)PYRIMIDINE-4-CARBOXAMIDE 95.00%
1G
$ 744.98

Alfa Aesar
2-(Trifluoromethyl)pyrimidine-4-carboxamide, 97%
1g
$ 300.00

Alfa Aesar
2-(Trifluoromethyl)pyrimidine-4-carboxamide, 97%
250mg
$ 101.00

Total 12 raw suppliers

Chemical Property of 2-(Trifluoromethyl)pyrimidine-4-carboxamide

Chemical Property:

Vapor Pressure:1.8E-10mmHg at 25°C
Boiling Point:508.8oC at 760 mmHg
Flash Point:261.5oC
PSA：68.87000
Density:1.45g/cm3
LogP:1.29460
XLogP3:0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:191.03064625
Heavy Atom Count:13
Complexity:206

Purity/Quality:

97% ^*data from raw suppliers

2-(Trifluoromethyl)pyrimidine-4-carboxamide ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN=C(N=C1C(=O)N)C(F)(F)F
Uses 2-(Trifluoromethyl)pyrimidine-4-carboxamide is used as pharmaceutical intermediate.

Technology Process of 2-(Trifluoromethyl)pyrimidine-4-carboxamide

There total 2 articles about 2-(Trifluoromethyl)pyrimidine-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 878745-51-8
methyl 2-(trifluoromethyl)pyrimidine-4-carboxylate

: 914348-10-0
2-(trifluoromethyl)pyrimidine-4-carboxamide

Guidance literature:: With ammonia; In methanol; at 50 ℃; for 16h;

Reference yield:

: 1514-96-1
4-chloro-2-(trifluoromethyl)pyrimidine

: 914348-10-0
2-(trifluoromethyl)pyrimidine-4-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; palladium diacetate; 1,1'-bis-(diphenylphosphino)ferrocene / 16 h / 60 °C / 3102.97 Torr

2: ammonia / methanol / 6 h / 50 °C

With 1,1'-bis-(diphenylphosphino)ferrocene; ammonia; palladium diacetate; triethylamine; In methanol;