6-Amino-7-methyl-9-pentofuranosyl-7,9-dihydro-8h-purin-8-one

Base Information

Chemical Name:6-Amino-7-methyl-9-pentofuranosyl-7,9-dihydro-8h-purin-8-one
CAS No.:27963-79-7
Molecular Formula:C₁₁H₁₅N₅O₅
Molecular Weight:297.271
Hs Code.:
NSC Number:127521
DSSTox Substance ID:DTXSID00950652
Mol file:27963-79-7.mol

Synonyms:27963-79-7;NSC127521;6-amino-7-methyl-9-pentofuranosyl-7,9-dihydro-8h-purin-8-one;DTXSID00950652;ZINC01715865;NSC-127521

Suppliers and Price of 6-Amino-7-methyl-9-pentofuranosyl-7,9-dihydro-8h-purin-8-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 6-Amino-7-methyl-9-pentofuranosyl-7,9-dihydro-8h-purin-8-one

Chemical Property:

Vapor Pressure:1.42E-15mmHg at 25°C
Boiling Point:606.7°Cat760mmHg
Flash Point:320.7°C
Density:1.73g/cm³
XLogP3:-2.3
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:2
Exact Mass:297.10731860
Heavy Atom Count:21
Complexity:426

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2=C(N=CN=C2N(C1=O)C3C(C(C(O3)CO)O)O)N

Technology Process of 6-Amino-7-methyl-9-pentofuranosyl-7,9-dihydro-8h-purin-8-one

There total 5 articles about 6-Amino-7-methyl-9-pentofuranosyl-7,9-dihydro-8h-purin-8-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 88420-72-8
7,8-dihydro-2',3'-O-isopropylidene-7-methyl-8-oxoadenosine

: 27963-79-7
7-methyl-8-oxoadenosine

Guidance literature:: With acetic acid; for 1.5h; Heating;
DOI:10.1055/s-1983-30542

Reference yield:

: 362-75-4
2',3'-isopropylidene adenosine

: 27963-79-7
7-methyl-8-oxoadenosine

Guidance literature:: Multi-step reaction with 4 steps

1: 72 percent / pyridine / Ambient temperature

2: 58 percent / N,N-dimethyl-acetamide / 18 h / 37 °C

3: 1.) 30percent H₂O₂, CH₃COOH, 2.) CH₃ONa / 1.) r.t., overnight, 2.) methanol, reflux, 24 h

4: 90 percent / 10percent CH₃COOOH / 1.5 h / Heating

With pyridine; peracetic acid; dihydrogen peroxide; sodium methylate; acetic acid; In N,N-dimethyl acetamide;

Reference yield:

: 39947-04-1
N-6-benzoyl-2',3'-O-isopropylideneadenosine

: 27963-79-7
7-methyl-8-oxoadenosine

Guidance literature:: Multi-step reaction with 3 steps

1: 58 percent / N,N-dimethyl-acetamide / 18 h / 37 °C

2: 1.) 30percent H₂O₂, CH₃COOH, 2.) CH₃ONa / 1.) r.t., overnight, 2.) methanol, reflux, 24 h

3: 90 percent / 10percent CH₃COOOH / 1.5 h / Heating

With peracetic acid; dihydrogen peroxide; sodium methylate; acetic acid; In N,N-dimethyl acetamide;