Spiro[piperidine-4,3'-[3H]pyrrolo[2,3-b]pyridin]-2'(1'H)-one

Base Information

Chemical Name:Spiro[piperidine-4,3'-[3H]pyrrolo[2,3-b]pyridin]-2'(1'H)-one
CAS No.:884049-52-9
Molecular Formula:C11H13N3O
Molecular Weight:203.24
Hs Code.:2933990090
Mol file:884049-52-9.mol

Synonyms:Spiro[piperidine-4,3'-[3H]pyrrolo[2,3-b]pyridin]-2'(1'H)-one;Spiro[piperidine-4,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one

Suppliers and Price of Spiro[piperidine-4,3'-[3H]pyrrolo[2,3-b]pyridin]-2'(1'H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Spiro[piperidine-4,3''-pyrrolo[2,3-B]pyridin]-2''(1''H)-one
2.5mg
$ 45.00

American Custom Chemicals Corporation
SPIRO[PIPERIDINE-4,3'-PYRROLO[2,3-B]PYRIDIN]-2'(1'H)-ONE 95.00%
5MG
$ 503.47

Ambeed
Spiro[piperidine-4,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one 98+%
1g
$ 600.00

Ambeed
Spiro[piperidine-4,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one 98+%
250mg
$ 283.00

AK Scientific
Spiro[piperidine-4,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one
1g
$ 1196.00

Total 13 raw suppliers

Chemical Property of Spiro[piperidine-4,3'-[3H]pyrrolo[2,3-b]pyridin]-2'(1'H)-one

Chemical Property:

Boiling Point:445.6±45.0 °C
PKA:12.05±0.20(Predicted)
Flash Point:223.3±28.7 °C
PSA：57.51000
Density:1.29±0.1 g/cm3(Predicted)
LogP:1.06880
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

97% ^*data from raw suppliers

Spiro[piperidine-4,3''-pyrrolo[2,3-B]pyridin]-2''(1''H)-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Spiro[piperidine-4,3'-[3H]pyrrolo[2,3-b]pyridin]-2'(1'H)-one

There total 16 articles about Spiro[piperidine-4,3'-[3H]pyrrolo[2,3-b]pyridin]-2'(1'H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 883984-92-7
3,4-dihydroxyspiro[cyclopent-3-ene-1,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one

: 884049-52-9
spiro[piperidine-4,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one

Guidance literature:: 3,4-dihydroxyspiro[cyclopent-3-ene-1,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one; With sodium periodate; In ethanol; water;

With ammonia; In ethanol; water;

With hydrogen; palladium dihydroxide; In ethanol; water; for 48h; under 2585.81 Torr;

Reference yield:

: 885031-86-7
tert-butyl 2'-oxo-1',2'-dihydro-1H-spiro[piperidine-4,3'-pyrrolo[2.3-b]pyridine]-1-carboxylate

: 884049-52-9
spiro[piperidine-4,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one

Guidance literature:: With hydrogenchloride; In water; ethyl acetate; at 20 ℃; for 3h;
DOI:10.1016/j.cclet.2011.01.042

Reference yield:

: tert-butyl 2'-oxo-1'-((2-(trimethylsilyl)ethoxy)methyl)-1',2'-dihydrospiro[piperidine-4,3'-pyrrolo[2,3-b]pyridine]-1-carboxylate

: 884049-52-9
spiro[piperidine-4,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one

: C₁₂H₁₅N₃O₂

Guidance literature:: tert-butyl 2'-oxo-1'-((2-(trimethylsilyl)ethoxy)methyl)-1',2'-dihydrospiro[piperidine-4,3'-pyrrolo[2,3-b]pyridine]-1-carboxylate; With hydrogenchloride; In 1,4-dioxane; at 23 ℃; for 1h; Inert atmosphere;

In ethylene glycol; at 70 ℃; for 15h; Inert atmosphere;
DOI:10.1021/jm4013906