3-Hydrazinyl-4-methoxypyridine dihydrochloride

Base Information

• Chemical Name: 3-Hydrazinyl-4-methoxypyridine dihydrochloride
• CAS No.: 120256-22-6
• Molecular Formula: C6H9N3O . 2ClH
• Molecular Weight: 212.076996
• DSSTox Substance ID: DTXSID70558149
• Mol file: 120256-22-6.mol

Synonyms:3-Hydrazinyl-4-methoxypyridine dihydrochloride;120256-22-6;(4-methoxypyridin-3-yl)hydrazine;dihydrochloride;DTXSID70558149;GS1740;3-Hydrazinyl-4-methoxypyridinedihydrochloride;3-hydrazinyl-4-methoxy-Pyridine hydrochloride;3-Hydrazinyl-4-methoxypyridine--hydrogen chloride (1/2)

Chemical Property of 3-Hydrazinyl-4-methoxypyridine dihydrochloride

Chemical Property:

• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 211.0279174
• Heavy Atom Count: 12
• Complexity: 99

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=NC=C1)NN.Cl.Cl

Technology Process of 3-Hydrazinyl-4-methoxypyridine dihydrochloride

There total 5 articles about 3-Hydrazinyl-4-methoxypyridine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

N-(4-methoxypyrid-3-yl)sydnone (120256-20-4) → 3-hydrazino-4-methoxypyridine dihydrochloride (120256-22-6)

Guidance literature:

With hydrogenchloride; In water; boiling water-bath;

Reference yield:

[(E)-4-Methoxy-pyridin-3-ylimino]-acetic acid butyl ester → 3-hydrazino-4-methoxypyridine dihydrochloride (120256-22-6)

Guidance literature:

Multi-step reaction with 4 steps

1: H₂ / 10percent Pd/C / H₂O / 1551.4 Torr / Ambient temperature

2: 87 percent / NaNO₂, conc. hydrochloric acid / 0 °C / pH 2

3: 92 percent / acetic anhydride / 0.5 h / boiling water-bath

4: 48 percent / conc. hydrochloric acid / H₂O / boiling water-bath

With hydrogenchloride; hydrogen; acetic anhydride; sodium nitrite; palladium on activated charcoal; In water;

Reference yield:

4-Methoxy-pyridin-3-ylamine; hydrochloride (120256-14-6) → 3-hydrazino-4-methoxypyridine dihydrochloride (120256-22-6)

Guidance literature:

Multi-step reaction with 5 steps

1: H₂O

2: H₂ / 10percent Pd/C / H₂O / 1551.4 Torr / Ambient temperature

3: 87 percent / NaNO₂, conc. hydrochloric acid / 0 °C / pH 2

4: 92 percent / acetic anhydride / 0.5 h / boiling water-bath

5: 48 percent / conc. hydrochloric acid / H₂O / boiling water-bath

With hydrogenchloride; hydrogen; acetic anhydride; sodium nitrite; palladium on activated charcoal; In water;

upstream raw materials:

N-(4-methoxypyrid-3-yl)sydnone

4-Methoxy-pyridin-3-ylamine; hydrochloride

N-(4-methoxypyrid-3-yl)glycine hydrochloride

N-nitroso-N-(4-methoxypyrid-3-yl)glycine dihydrochloride