1-Benzyl-2,2-dimethylpiperidin-4-one

Base Information

Chemical Name:1-Benzyl-2,2-dimethylpiperidin-4-one
CAS No.:117623-46-8
Molecular Formula:C14H19NO
Molecular Weight:217.311
Hs Code.:2933399090
DSSTox Substance ID:DTXSID80399000
Wikidata:Q82201290
Mol file:117623-46-8.mol

Synonyms:1-benzyl-2,2-dimethylpiperidin-4-one;117623-46-8;1-benzyl-2,2-dimethyl-piperidin-4-one;4-Piperidinone, 2,2-dimethyl-1-(phenylmethyl)-;SCHEMBL3061605;DTXSID80399000;QXCCSKIRCJMSMM-UHFFFAOYSA-N;MFCD01211801;AKOS016005451;1-Benzyl-2,2-dimethyl-4-piperidinone;SB31019;s11059;BB 0261997;CS-0197694;2,2-dimethyl-1-(phenylmethyl)-4-piperidinone;A893322

Suppliers and Price of 1-Benzyl-2,2-dimethylpiperidin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Benzyl-2,2-dimethylpiperidin-4-one
50mg
$ 110.00

J&W Pharmlab
1-Benzyl-2,2-dimethyl-piperidin-4-one 98%
500mg
$ 398.00

J&W Pharmlab
1-Benzyl-2,2-dimethyl-piperidin-4-one 98%
5g
$ 2770.00

J&W Pharmlab
1-Benzyl-2,2-dimethyl-piperidin-4-one 98%
1g
$ 698.00

J&W Pharmlab
1-Benzyl-2,2-dimethyl-piperidin-4-one 98%
100mg
$ 175.00

J&W Pharmlab
1-Benzyl-2,2-dimethyl-piperidin-4-one 98%
50mg
$ 137.00

J&W Pharmlab
1-Benzyl-2,2-dimethyl-piperidin-4-one 98%
250mg
$ 249.00

Crysdot
1-Benzyl-2,2-dimethylpiperidin-4-one 95+%
250mg
$ 236.00

Crysdot
1-Benzyl-2,2-dimethylpiperidin-4-one 95+%
1g
$ 680.00

Chemenu
1-benzyl-2,2-dimethylpiperidin-4-one 95%
1g
$ 282.00

Total 13 raw suppliers

Chemical Property of 1-Benzyl-2,2-dimethylpiperidin-4-one

Chemical Property:

Boiling Point:318.0±22.0 °C(Predicted)
PKA:7.19±0.40(Predicted)
PSA：20.31000
Density:1.031±0.06 g/cm3(Predicted)
LogP:2.56800
Storage Temp.:2-8°C
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:217.146664230
Heavy Atom Count:16
Complexity:254

Purity/Quality:

97% ^*data from raw suppliers

1-Benzyl-2,2-dimethylpiperidin-4-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CC(=O)CCN1CC2=CC=CC=C2)C

Technology Process of 1-Benzyl-2,2-dimethylpiperidin-4-one

There total 5 articles about 1-Benzyl-2,2-dimethylpiperidin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: N-(1-benzyl-2,2-dimethyl-1,2,3,4-tetrahydropyridin-4-ylidene)piperidin-1-ium bromide

: 117623-46-8
1-benzyl-2,2-dimethylpiperidin-4-one

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; at 35 ℃; chemoselective reaction;
DOI:10.1016/j.tet.2021.132189

Reference yield:

: N-(2,2-dimethyl-6-methylsulfanyl-1,2,3,4-tetrahydropyridin-4-yliden)piperidin-1-ium iodide

: 117623-46-8
1-benzyl-2,2-dimethylpiperidin-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: Raney nickel / ethanol / 20 °C

2: potassium carbonate / chloroform / 20 °C

3: lithium aluminium tetrahydride / diethyl ether / 35 °C

With lithium aluminium tetrahydride; potassium carbonate; In diethyl ether; ethanol; chloroform;
DOI:10.1016/j.tet.2021.132189

Reference yield:

: N-(2,2-dimethyl-1,2,3,4-tetrahydropyridin-4-yliden)piperidin-1-ium iodide

: 117623-46-8
1-benzyl-2,2-dimethylpiperidin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / chloroform / 20 °C

2: lithium aluminium tetrahydride / diethyl ether / 35 °C

With lithium aluminium tetrahydride; potassium carbonate; In diethyl ether; chloroform;
DOI:10.1016/j.tet.2021.132189