5-(chloromethyl)-4-methyl-2-phenyl-1,3-oxazole

Base Information

Chemical Name:5-(chloromethyl)-4-methyl-2-phenyl-1,3-oxazole
CAS No.:625106-10-7
Molecular Formula:C₁₁H₁₀ClNO
Molecular Weight:207.659
Hs Code.:
Mol file:625106-10-7.mol

Synonyms:5-(chloromethyl)-4-methyl-2-phenyl-1,3-oxazole;5-(Chloromethyl)-4-methyl-2-phenyl-1,3-oxazole 95%

Suppliers and Price of 5-(chloromethyl)-4-methyl-2-phenyl-1,3-oxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
5-(Chloromethyl)-4-methyl-2-phenyl-1,3-oxazole
10g
$ 4220.00

AK Scientific
5-(Chloromethyl)-4-methyl-2-phenyl-1,3-oxazole
250mg
$ 519.00

Total 2 raw suppliers

Chemical Property of 5-(chloromethyl)-4-methyl-2-phenyl-1,3-oxazole

Chemical Property:

PSA：26.03000
LogP:3.38880

Purity/Quality:: 5-(Chloromethyl)-4-methyl-2-phenyl-1,3-oxazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-(chloromethyl)-4-methyl-2-phenyl-1,3-oxazole

There total 5 articles about 5-(chloromethyl)-4-methyl-2-phenyl-1,3-oxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4620-52-4
Ethyl 4-methyl-2-phenyloxazole-5-carboxylate

: 625106-10-7
5-chloromethyl-4-methyl-2-phenyl-oxazole

Guidance literature:: Multi-step reaction with 2 steps

1: SMEAH / tetrahydrofuran / 1 h / 0 °C

2: SOCl₂ / toluene / 0 °C

With thionyl chloride; sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; toluene;
DOI:10.1055/s-2004-834862

Reference yield:

: 248924-06-3
(4-methyl-2-phenyloxazol-5-yl)methanol

: 625106-10-7
5-chloromethyl-4-methyl-2-phenyl-oxazole

Guidance literature:: With thionyl chloride; In toluene; at 0 ℃;
DOI:10.1055/s-2004-834862

Reference yield:

: 55-21-0,27208-38-4
benzamide

: 625106-10-7
5-chloromethyl-4-methyl-2-phenyl-oxazole

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol / 16 h / Reflux

2: sodium tetrahydroborate / tetrahydrofuran; methanol / 0.5 h / Reflux

3: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 4 h / 40 °C

With sodium tetrahydroborate; thionyl chloride; N,N-dimethyl-formamide; In tetrahydrofuran; methanol; ethanol; dichloromethane;
DOI:10.1016/j.ejmech.2016.02.040