2-Amino-7-nitro-fluoren-9-one

Base Information

• Chemical Name: 2-Amino-7-nitro-fluoren-9-one
• CAS No.: 88387-73-9
• Molecular Formula: C13H8N2O3
• Molecular Weight: 240.2142
• NSC Number: 90677
• DSSTox Substance ID: DTXSID80398356
• Nikkaji Number: J36.303K
• Wikidata: Q82200265
• ChEMBL ID: CHEMBL1881462
• Mol file: 88387-73-9.mol

Synonyms:MLS002695002;88387-73-9;2-amino-7-nitro-fluoren-9-one;NSC90677;NCIOpen2_005553;CHEMBL1881462;DTXSID80398356;HMS3085C20;7-Amino-2-nitro-9H-fluoren-9-one;NSC-90677;SMR001560915

Chemical Property of 2-Amino-7-nitro-fluoren-9-one

Chemical Property:

• Vapor Pressure: 1.09E-10mmHg at 25°C
• Boiling Point: 514.3°Cat760mmHg
• Flash Point: 264.8°C
• Density: 1.511g/cm³
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 240.05349212
• Heavy Atom Count: 18
• Complexity: 379

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C=C1N)C(=O)C3=C2C=CC(=C3)[N+](=O)[O-]

Technology Process of 2-Amino-7-nitro-fluoren-9-one

There total 9 articles about 2-Amino-7-nitro-fluoren-9-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

9-Hydroxy-2,7-dinitrofluorene (1858-80-6) + acetyl CoA → 9-oxo-2-acetylamino-7-nitrofluorene (7151-59-9) + 9-Oxo-2-amino-7-nitrofluorene (88387-73-9)

Guidance literature:

With 1,4-dihydronicotinamide adenine dinucleotide; calf thymus DNA; Sprague-Dawley rat liver cytosol; In dimethyl sulfoxide; at 37 ℃; for 21h; pH=7.0; Further Variations:; Catalysts; Product distribution; Enzymatic reaction;

DOI:10.1021/tx010172p

Reference yield:

2,7-dinitro-9-fluorenone (31551-45-8) + acetyl CoA → 9-oxo-2-acetylamino-7-nitrofluorene (7151-59-9) + 9-Oxo-2-amino-7-nitrofluorene (88387-73-9) + 9-hydroxy-2-amino-7-nitrofluorene

Guidance literature:

With 1,4-dihydronicotinamide adenine dinucleotide; calf thymus DNA; Sprague-Dawley rat liver cytosol; In dimethyl sulfoxide; at 37 ℃; for 21h; pH=7.0; Further Variations:; Catalysts; Product distribution; Enzymatic reaction;

DOI:10.1021/tx010172p

Reference yield:

2-amino-9-fluorenone (3096-57-9) → 9-Oxo-2-amino-7-nitrofluorene (88387-73-9)

Guidance literature:

With sulfuric acid; nitric acid; at 0 ℃;

upstream raw materials:

2-amino-9-fluorenone

2-acetylaminofluorene

2-acetylamino-9-fluorenone

2,7-dinitro-9-fluorenone

Downstream raw materials:

2,7-diaminofluoren-9-one

9-oxo-2-acetylamino-7-nitrofluorene