(S)-3-aMino-1-hydroxy-3,4-dihydroquinolin-2(1H)-one hydrochloride

Base Information

• Chemical Name: (S)-3-aMino-1-hydroxy-3,4-dihydroquinolin-2(1H)-one hydrochloride
• CAS No.: 177943-33-8
• Molecular Formula: C9H10N2O2.ClH
• Molecular Weight: 214.652
• Hs Code.: 2933790090
• Mol file: 177943-33-8.mol

Synonyms:(3S)-3-Amino-1-hydroxy-3,4-dihydroquinolin-2(1H)-one;

Chemical Property of (S)-3-aMino-1-hydroxy-3,4-dihydroquinolin-2(1H)-one hydrochloride

Chemical Property:

• PSA: 66.56000
• LogP: 1.85950
• Storage Temp.: room temp
• Solubility.: H2O: soluble20mg/mL, clear

Purity/Quality:

98%,99%, ^*data from raw suppliers

PF-04859989 hydrochloride ≥98% (HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-3-aMino-1-hydroxy-3,4-dihydroquinolin-2(1H)-one hydrochloride

There total 1 articles about (S)-3-aMino-1-hydroxy-3,4-dihydroquinolin-2(1H)-one hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

(2S)-2-amino-3-(2-nitrophenyl)propanoic acid (1991-82-8,35378-63-3,19883-75-1) → (3S)-3-amino-1-hydroxy-3,4-dihydroquinolin-2(1H)-one hydrochloride (177943-33-8)

Guidance literature:

(2S)-2-amino-3-(2-nitrophenyl)propanoic acid; With platinum on carbon; hydrogen; In pyridine; at 10 ℃; for 50h; under 1551.49 Torr;

With hydrogenchloride; In methanol; at 20 ℃; for 0.5h;

DOI:10.1021/ml200204m

upstream raw materials:

(2S)-2-amino-3-(2-nitrophenyl)propanoic acid

Refernces