tert-Butyl 4-((4-cyano-2-nitrophenyl)amino)piperidine-1-carboxylate

Base Information

Chemical Name:tert-Butyl 4-((4-cyano-2-nitrophenyl)amino)piperidine-1-carboxylate
CAS No.:320406-05-1
Molecular Formula:C17H22N4O4
Molecular Weight:346.386
Hs Code.:2933399090
DSSTox Substance ID:DTXSID40594291
Wikidata:Q82489089
Mol file:320406-05-1.mol

Synonyms:320406-05-1;tert-Butyl 4-((4-cyano-2-nitrophenyl)amino)piperidine-1-carboxylate;tert-butyl 4-(4-cyano-2-nitroanilino)piperidine-1-carboxylate;TERT-BUTYL 4-((4-CYANO-2-NITROPHENYL)-AMINO)PIPERIDINE-1-CARBOXYLATE;SCHEMBL7190957;SCHEMBL14008588;DTXSID40594291;tert-Butyl4-((4-cyano-2-nitrophenyl)amino)piperidine-1-carboxylate;DB-173876

Suppliers and Price of tert-Butyl 4-((4-cyano-2-nitrophenyl)amino)piperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
tert-Butyl 4-((4-cyano-2-nitrophenyl)-amino)piperidine-1-carboxylate 95+%
1g
$ 1647.00

Matrix Scientific
tert-Butyl 4-((4-cyano-2-nitrophenyl)-amino)piperidine-1-carboxylate 95+%
250mg
$ 742.00

Crysdot
tert-Butyl4-((4-cyano-2-nitrophenyl)amino)piperidine-1-carboxylate 95+%
1g
$ 772.00

Chemenu
tert-Butyl4-((4-cyano-2-nitrophenyl)-amino)piperidine-1-carboxylate 95%
1g
$ 729.00

American Custom Chemicals Corporation
TERT-BUTYL-4-((4-CYANO-2-NITROPHENYL)AMINO)PIPERIDINE-1-CARBOXYLATE 95.00%
5MG
$ 499.07

Alichem
tert-Butyl4-((4-cyano-2-nitrophenyl)amino)piperidine-1-carboxylate
1g
$ 646.84

AK Scientific
tert-Butyl4-((4-cyano-2-nitrophenyl)amino)piperidine-1-carboxylate
1g
$ 2273.00

AK Scientific
tert-Butyl4-((4-cyano-2-nitrophenyl)amino)piperidine-1-carboxylate
250mg
$ 1051.00

Total 4 raw suppliers

Chemical Property of tert-Butyl 4-((4-cyano-2-nitrophenyl)amino)piperidine-1-carboxylate

Chemical Property:

Boiling Point:500.3±50.0 °C(Predicted)
PKA:-2.04±0.40(Predicted)
PSA：111.18000
Density:1.26±0.1 g/cm3(Predicted)
LogP:3.81198
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:346.16410520
Heavy Atom Count:25
Complexity:537

Purity/Quality:

95+% ^*data from raw suppliers

tert-Butyl 4-((4-cyano-2-nitrophenyl)-amino)piperidine-1-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC(CC1)NC2=C(C=C(C=C2)C#N)[N+](=O)[O-]

Technology Process of tert-Butyl 4-((4-cyano-2-nitrophenyl)amino)piperidine-1-carboxylate

There total 2 articles about tert-Butyl 4-((4-cyano-2-nitrophenyl)amino)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1009-35-4
4-fluoro-3-nitrobenzonitrile

: 87120-72-7
1-(tert-butoxycarbonyl)-4-aminopiperidine

: 320406-05-1
tert-butyl 4-((4-cyano-2-nitrophenyl)amino)piperidine-1-carboxylate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 72h;

Reference yield:

: 320406-05-1
tert-butyl 4-((4-cyano-2-nitrophenyl)amino)piperidine-1-carboxylate

Guidance literature:

Reference yield:

: 320406-05-1
tert-butyl 4-((4-cyano-2-nitrophenyl)amino)piperidine-1-carboxylate

: 1037834-87-9
1-{1-[2-(4-chlorophenyl)-2-oxoethyl]piperidin-4-yl}-5-(1H-tetrazol-5-yl)-1,3-dihydro-2H-benzimidazol-2-one

Guidance literature:: Multi-step reaction with 4 steps

1.1: cyclohexene / palladium 10% on activated carbon / ethanol / 8 h / 50 °C

2.1: dmap / tetrahydrofuran / 2.5 h / 60 °C

3.1: trimethylsilylazide; di(n-butyl)tin oxide / toluene / 110 °C

4.1: trifluoroacetic acid / dichloromethane / 2 h / 20 °C

4.2: 1 h / 0 °C

With dmap; trimethylsilylazide; di(n-butyl)tin oxide; trifluoroacetic acid; cyclohexene; palladium 10% on activated carbon; In tetrahydrofuran; ethanol; dichloromethane; toluene;