Alisporivir

Base Information

Chemical Name:Alisporivir
CAS No.:254435-95-5
Deprecated CAS:860642-18-8
Molecular Formula:C63H113N11O12
Molecular Weight:1216.6378
Hs Code.:
European Community (EC) Number:807-328-0
UNII:VBP9099AA6
ChEMBL ID:CHEMBL1651956
DSSTox Substance ID:DTXSID401027752
Metabolomics Workbench ID:144554
NCI Thesaurus Code:C169774
Nikkaji Number:J3.340.094B
Wikidata:Q4727236
Wikipedia:Alisporivir
Mol file:254435-95-5.mol

Synonyms:alisporivir;DEBIO-025;MeAla(3)EtVal(4)-cyclosporin;UNIL 025;UNIL-025;UNIL025

Suppliers and Price of Alisporivir

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 26 raw suppliers

Chemical Property of Alisporivir

Chemical Property:

PSA：278.80000
LogP:4.53800
XLogP3:7.9
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:15
Exact Mass:1215.85701808
Heavy Atom Count:86
Complexity:2360

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCC1C(=O)N(C(C(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)C(C(C)CC=CC)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)C(C)C)CC)C)C
Isomeric SMILES:CC[C@H]1C(=O)N([C@@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)C(C)C)CC)C)C
Recent ClinicalTrials:Evaluation of Alisporivir for the Treatment of Hospitalised Patients With Infections Due to SARS-CoV-2 (COVID-19)
Recent EU Clinical Trials:Evaluation of the efficacy, safety and tolerability of alisporivir for the treatment of hospitalised patients with infections due to SARS-CoV-2 (COVID-19).

Technology Process of Alisporivir

There total 1 articles about Alisporivir which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 1038781-14-4
H-D-MeAla-EtVal-Val-MeLeu-Ala-D-Ala-MeLeu-MeLeu-MeVal-MeBmt-Abu-OH

: 254435-95-5
alisporivir

Guidance literature:: H-D-MeAla-EtVal-Val-MeLeu-Ala-D-Ala-MeLeu-MeLeu-MeVal-MeBmt-Abu-OH; With 2,4,6-trimethyl-pyridine; ((3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V); In dichloromethane; for 72h;

With water; sodium carbonate; In dichloromethane;