N-[(2S)-2-AMINO-2-PHENYLETHYL]-CARBAMIC ACID 1,1-DIMETHYLETHYL ESTER

Base Information

Chemical Name:N-[(2S)-2-AMINO-2-PHENYLETHYL]-CARBAMIC ACID 1,1-DIMETHYLETHYL ESTER
CAS No.:943322-87-0
Molecular Formula:C13H20N2O2
Molecular Weight:236.314
Hs Code.:2924299090
Mol file:943322-87-0.mol

Synonyms:N-((2S)-2-AMINO-2-PHENYLETHYL)(TERT-BUTOXY)CARBOXAMIDE;N-[(2S)-2-AMINO-2-PHENYLETHYL]-CARBAMIC ACID 1,1-DIMETHYLETHYL ESTER;(S)-tert-Butyl (2-aMino-2-phenylethyl)carbaMate;CarbaMic acid, [(2S)-2-aMino-2-phenylethyl]-, 1,1-diMethylethyl ester;N-[(S)-2-AMino-2-phenylethyl]carbaMic acid tert-butyl ester;(S)-N2-Boc-1-phenylethylenediaMine

Suppliers and Price of N-[(2S)-2-AMINO-2-PHENYLETHYL]-CARBAMIC ACID 1,1-DIMETHYLETHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
N-((2s)-2-amino-2-phenylethyl)(tert-butoxy)carboxamide 95
1g
$ 583.00

J&W Pharmlab
(S)-(2-Amino-2-phenyl-ethyl)-carbamicacidtert-butylester 97%
100mg
$ 125.00

J&W Pharmlab
(S)-(2-Amino-2-phenyl-ethyl)-carbamicacidtert-butylester 97%
50mg
$ 110.00

Crysdot
(S)-tert-Butyl(2-amino-2-phenylethyl)carbamate 97%
5g
$ 772.00

Crysdot
(S)-tert-Butyl(2-amino-2-phenylethyl)carbamate 97%
1g
$ 257.00

Crysdot
(S)-tert-Butyl(2-amino-2-phenylethyl)carbamate 97%
25g
$ 2426.00

Crysdot
(S)-tert-Butyl(2-amino-2-phenylethyl)carbamate 97%
10g
$ 1238.00

Chemenu
(S)-N2-Boc-1-phenylethylenediamine 95+%
10g
$ 1169.00

Chemenu
(S)-N2-Boc-1-phenylethylenediamine 95+%
1g
$ 243.00

Chemenu
(S)-N2-Boc-1-phenylethylenediamine 95+%
5g
$ 729.00

Total 22 raw suppliers

Chemical Property of N-[(2S)-2-AMINO-2-PHENYLETHYL]-CARBAMIC ACID 1,1-DIMETHYLETHYL ESTER

Chemical Property:

PSA：67.84000
LogP:3.11580
Storage Temp.:Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

Purity/Quality:

99%, ^*data from raw suppliers

N-((2s)-2-amino-2-phenylethyl)(tert-butoxy)carboxamide 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-[(2S)-2-AMINO-2-PHENYLETHYL]-CARBAMIC ACID 1,1-DIMETHYLETHYL ESTER

There total 13 articles about N-[(2S)-2-AMINO-2-PHENYLETHYL]-CARBAMIC ACID 1,1-DIMETHYLETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 1374635-42-3
tert-butyl N-[(2S)-2-(benzyloxycarbonylamino)-2-phenyl-ethyl]carbamate

: 943322-87-0
tert-butyl N-[(2S)-2-amino-2-phenylethyl]carbamate

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In 1,4-dioxane; for 24h;
DOI:10.1039/c2ob25693b

Reference yield:

: 2900-27-8
(2S)-2-[(tert-butoxycarbonyl)amino]-2-phenylethanoic acid

: 943322-87-0
tert-butyl N-[(2S)-2-amino-2-phenylethyl]carbamate

Guidance literature:: Multi-step reaction with 8 steps

1.1: triethylamine / tetrahydrofuran

2.1: triethylamine / dichloromethane

3.1: sodium azide / N,N-dimethyl-formamide / 60 °C

4.1: hydrogenchloride; methanol

5.1: triethylamine / dichloromethane

6.1: triphenylphosphine / tetrahydrofuran / 8 h / Reflux

6.2: 16 h / Reflux

7.1: triethylamine / dichloromethane / 24 h / 20 °C

8.1: palladium 10% on activated carbon; hydrogen / 1,4-dioxane / 24 h

With hydrogenchloride; methanol; sodium azide; palladium 10% on activated carbon; hydrogen; triethylamine; triphenylphosphine; In tetrahydrofuran; 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/c2ob25693b