3-(Bromomethyl)-4-methylpyridine

Base Information

• Chemical Name: 3-(Bromomethyl)-4-methylpyridine
• CAS No.: 120277-12-5
• Molecular Formula: C7H8BrN
• Molecular Weight: 186.05
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID70565131
• Wikidata: Q82450075
• Mol file: 120277-12-5.mol

Synonyms:3-(BROMOMETHYL)-4-METHYLPYRIDINE;120277-12-5;SCHEMBL9138822;DTXSID70565131;AKOS006324952;SB54145;EN300-1915172;6-(TRIFLUOROMETHYL)QUINOLINE,95%MIN(HPLC);A892277;W-205088

Chemical Property of 3-(Bromomethyl)-4-methylpyridine

Chemical Property:

• Vapor Pressure: 0.0317mmHg at 25°C
• Boiling Point: 251.9°C at 760 mmHg
• PKA: 4.99±0.18(Predicted)
• Flash Point: 106.1°C
• PSA: 12.89000
• Density: 1.448g/cm³
• LogP: 2.28490
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 184.98401
• Heavy Atom Count: 9
• Complexity: 85

Purity/Quality:

97% ^*data from raw suppliers

3-(bromomethyl)-4-methylpyridine 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=NC=C1)CBr

Technology Process of 3-(Bromomethyl)-4-methylpyridine

There total 1 articles about 3-(Bromomethyl)-4-methylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,4-Lutidin (583-58-4) → 3-(bromomethyl)-4-methylpyridine (120277-12-5)

Guidance literature:

With N-Bromosuccinimide; In tetrachloromethane;

DOI:10.1021/jm00107a023

Reference yield: 92.0%

4-(2-(4-((1H-benzo[d]imidazol-2-yl)amino)piperidin-1-yl)ethyl)benzonitrile + 3-(bromomethyl)-4-methylpyridine (120277-12-5) → 4-(2-(4-((1-((6-methylpyridin-3-yl)methyl)-1H-benzo[d]imidazol-2-yl)amino)piperidin-1-yl) ethyl)benzonitrile

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 70 ℃; for 12h; Inert atmosphere;

DOI:10.1021/acsmedchemlett.1c00328

upstream raw materials:

3,4-Lutidin