5-(4-(azetidin-3-yloxy)-3-methoxyphenyl)-2-(4-chlorophenyl)thiazolo[5,4-c]pyridin-4(5H)-one

Base Information

Chemical Name:5-(4-(azetidin-3-yloxy)-3-methoxyphenyl)-2-(4-chlorophenyl)thiazolo[5,4-c]pyridin-4(5H)-one
CAS No.:1035218-87-1
Molecular Formula:C22H18ClN3O3S
Molecular Weight:476.383
Hs Code.:

Synonyms:LSN-2606297;5-(4-(azetidin-3-yloxy)-3-Methoxyphenyl)-2-(4-chlorophenyl)thiazolo[5,4-c]pyridin-4(5H)-one;5-[4-(azetidin-3-yloxy)-3-methoxyphenyl]-2-(4-chlorophenyl)-[1,3]thiazolo[5,4-c]pyridin-4-one

Suppliers and Price of 5-(4-(azetidin-3-yloxy)-3-methoxyphenyl)-2-(4-chlorophenyl)thiazolo[5,4-c]pyridin-4(5H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 5-(4-(azetidin-3-yloxy)-3-methoxyphenyl)-2-(4-chlorophenyl)thiazolo[5,4-c]pyridin-4(5H)-one

Chemical Property:

PSA：93.62000
LogP:4.45560

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-(4-(azetidin-3-yloxy)-3-methoxyphenyl)-2-(4-chlorophenyl)thiazolo[5,4-c]pyridin-4(5H)-one

There total 2 articles about 5-(4-(azetidin-3-yloxy)-3-methoxyphenyl)-2-(4-chlorophenyl)thiazolo[5,4-c]pyridin-4(5H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1035219-47-6
3-(4-{[2-(4-chlorophenyl)-4-(2,2-dimethoxyethyl)thiazole-5-carbonyl]amino}-2-methoxyphenoxy)azetidine-1-carboxylic acid tert-butyl ester

: 1035218-87-1
5-[4-(azetidin-3-yloxy)-3-methoxyphenyl]-2-(4-chlorophenyl)-5H-thiazolo[5,4-c]pyridin-4-one hydrochloride

Guidance literature:: With hydrogenchloride; In ethanol; water; for 1h; Product distribution / selectivity; Heating / reflux;

Reference yield: 96.0%

: 1035219-73-8
3-{4-[2-(4-chlorophenyl)-4-oxo-4H-thiazolo[5,4-c]pyridin-5-yl]-2-methoxyphenoxy}azetidine-1-carboxylic acid tert-butyl ester

: 1035218-87-1
5-[4-(azetidin-3-yloxy)-3-methoxyphenyl]-2-(4-chlorophenyl)-5H-thiazolo[5,4-c]pyridin-4-one hydrochloride

Guidance literature:: With hydrogenchloride; In propan-1-ol; water; at 20 - 65 ℃; for 16h; Product distribution / selectivity;

Reference yield: 81.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 1035218-87-1
5-[4-(azetidin-3-yloxy)-3-methoxyphenyl]-2-(4-chlorophenyl)-5H-thiazolo[5,4-c]pyridin-4-one hydrochloride

: 1035218-91-7
2-(4-chlorophenyl)-5-[3-methoxy-4-(1-methylazetidin-3-yloxy)phenyl]-5H-thiazolo[5,4-c]pyridin-4-one

Guidance literature:: formaldehyd; 5-[4-(azetidin-3-yloxy)-3-methoxyphenyl]-2-(4-chlorophenyl)-5H-thiazolo[5,4-c]pyridin-4-one hydrochloride; With sodium cyanoborohydride; acetic acid; In methanol; water; at 15 - 20 ℃; for 15h;

With water; sodium hydrogencarbonate; In methanol; at 5 - 20 ℃; for 1h; Product distribution / selectivity;