4-Isoxazolecarboxylic acid, 5-(4-broMophenyl)-3-Methyl-, ethyl e

Base Information

Chemical Name:4-Isoxazolecarboxylic acid, 5-(4-broMophenyl)-3-Methyl-, ethyl e
CAS No.:917388-58-0
Molecular Formula:C13H12BrNO3
Molecular Weight:310.147
Hs Code.:
Mol file:917388-58-0.mol

Synonyms:5-(4-BROMOPHENYL)-3-METHYL-4-ISOXAZOLECARBOXYLIC ACID ETHYL ESTER;Y6500;Ethyl 5-(4-bromophenyl)-3-methylisoxazole-4-carboxylate;

Suppliers and Price of 4-Isoxazolecarboxylic acid, 5-(4-broMophenyl)-3-Methyl-, ethyl e

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 4-Isoxazolecarboxylic acid, 5-(4-broMophenyl)-3-Methyl-, ethyl e

Chemical Property:

PSA：52.33000
LogP:3.58920

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-Isoxazolecarboxylic acid, 5-(4-broMophenyl)-3-Methyl-, ethyl e

There total 2 articles about 4-Isoxazolecarboxylic acid, 5-(4-broMophenyl)-3-Methyl-, ethyl e which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 893643-73-7
2-(4-bromobenzoyl)-3-carbonylbutyrate ethyl ester

: 917388-58-0
5-(4-bromophenyl)-3-methylisoxazole-4-carboxylic acid ethyl ester

Guidance literature:: With hydroxylamine hydrochloride; In ethanol; water; at 60 ℃;

Reference yield:

: 141-97-9
ethyl acetoacetate

: 586-75-4
4-chlorobenzoyl chloride

: 917388-58-0
5-(4-bromophenyl)-3-methylisoxazole-4-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / water; Petroleum ether / 0.5 h / 0 °C

2: hydroxylamine hydrochloride / water; ethanol / 16 h / 60 °C

With hydroxylamine hydrochloride; sodium hydroxide; In ethanol; water; Petroleum ether;

Reference yield: 96.0%

: 917388-58-0
5-(4-bromophenyl)-3-methylisoxazole-4-carboxylic acid ethyl ester

: 91182-60-4
5-(4-bromophenyl)-3-methylisoxazole-4-carboxylic acid

Guidance literature:: 5-(4-bromophenyl)-3-methylisoxazole-4-carboxylic acid ethyl ester; With lithium hydroxide; water; In tetrahydrofuran; at 20 ℃;

With oxalic acid; In water; pH=~ 4;