4-Isoxazolecarboxylic acid, 3-ethyl-5-(trifluoroMethyl)-, ethyl

Base Information

• Chemical Name: 4-Isoxazolecarboxylic acid, 3-ethyl-5-(trifluoroMethyl)-, ethyl
• CAS No.: 363617-95-2
• Molecular Formula: C9H10F3NO3
• Molecular Weight: 237.18
• Mol file: 363617-95-2.mol

Synonyms:4-Isoxazolecarboxylic acid, 3-ethyl-5-(trifluoroMethyl)-, ethyl;3-ethyl-5-(trifluoromethyl)-4-Isoxazolecarboxylic acid ethyl ester;4-Isoxazolecarboxylic acid, 3-ethyl-5-(trifluoroMethyl)-, ethyl ester

Chemical Property of 4-Isoxazolecarboxylic acid, 3-ethyl-5-(trifluoroMethyl)-, ethyl

Chemical Property:

• Boiling Point: 287.0±40.0 °C(Predicted)
• PKA: -5.39±0.50(Predicted)
• Density: 1.273±0.06 g/cm3(Predicted)

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Isoxazolecarboxylic acid, 3-ethyl-5-(trifluoroMethyl)-, ethyl

There total 1 articles about 4-Isoxazolecarboxylic acid, 3-ethyl-5-(trifluoroMethyl)-, ethyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

1-Nitropropane (108-03-2) + ethyl 3-trifluoromethyl-3-pyrrolidino-acrylate → 4-ethoxycarbonyl-3-ethyl-5-trifluoromethyl-isoxazole (363617-95-2)

Guidance literature:

1-Nitropropane; ethyl 3-trifluoromethyl-3-pyrrolidino-acrylate; With triethylamine; trichlorophosphate; In chloroform; at 20 ℃; for 72h;

With hydrogenchloride; at 20 ℃;

DOI:10.1016/S0040-4020(01)00522-1

upstream raw materials:

1-Nitropropane

Refernces