(3S,4R)-4-(4-fluorophenyl)oxolan-3-aMine

Base Information

Chemical Name:(3S,4R)-4-(4-fluorophenyl)oxolan-3-aMine
CAS No.:1063733-97-0
Molecular Formula:C10H12FNO
Molecular Weight:181.21
Hs Code.:
Mol file:1063733-97-0.mol

Synonyms:(3S,4R)-4-(4-fluorophenyl)oxolan-3-aMine

Suppliers and Price of (3S,4R)-4-(4-fluorophenyl)oxolan-3-aMine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
rel-(3R,4S)-4-(4-Fluorophenyl)tetrahydro-3-furanamine
5g
$ 7590.00

Total 2 raw suppliers

Chemical Property of (3S,4R)-4-(4-fluorophenyl)oxolan-3-aMine

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

rel-(3R,4S)-4-(4-Fluorophenyl)tetrahydro-3-furanamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses rel-(3R,4S)-4-(4-Fluorophenyl)tetrahydro-3-furanamine, is a building block used in the synthesis of other chemical compounds, such as Selective Inhibitors of 3-Phosphoinositide-Dependent Kinase (PDK1).

Technology Process of (3S,4R)-4-(4-fluorophenyl)oxolan-3-aMine

There total 6 articles about (3S,4R)-4-(4-fluorophenyl)oxolan-3-aMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (±)-cis-2-[4-(4-fluorophenyl)tetrahydrofuran-3-yl]isoindoline-1,3-dione

: 1063733-97-0,1365937-32-1
(±)-cis-4-(4-fluorophenyl)tetrahydrofuran-3-amine

Guidance literature:: With hydrazine; In toluene; at 90 ℃; Inert atmosphere;
DOI:10.1021/jm201019k

Reference yield:

: C₁₅H₂₀FNO₃

: 1063733-97-0,1365937-32-1
C₁₀H₁₂FNO

Guidance literature:: Multi-step reaction with 2 steps

1: chiralpak AD-H / methanol; carbon dioxide / Inert atmosphere

2: hydrogenchloride / Inert atmosphere

With hydrogenchloride; In methanol; carbon dioxide;
DOI:10.1021/jm201019k

Reference yield:

: (±)-trans-4-(4-fluorophenyl)tetrahydrofuran-3-ol

: 1063733-97-0,1365937-32-1
(±)-cis-4-(4-fluorophenyl)tetrahydrofuran-3-amine

Guidance literature:: Multi-step reaction with 2 steps

1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

2: hydrazine / toluene / 90 °C / Inert atmosphere

With di-isopropyl azodicarboxylate; triphenylphosphine; hydrazine; In tetrahydrofuran; toluene;
DOI:10.1021/jm201019k