4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]benzoic Acid

Base Information

Chemical Name:4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]benzoic Acid
CAS No.:1044598-91-5
Molecular Formula:C26H31ClN2O2
Molecular Weight:438.997
Hs Code.:2933599090
Mol file:1044598-91-5.mol

Synonyms:4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]benzoic Acid;4-[4-[[2-(4-Chlorophenyl)-5,5-diMethyl-1-cyclohexenyl]Methyl]-1-;4-(4-{[2-(4-chlorophenyl)-5,5-diMethylcyclohex-1-en-1-yl]Methyl}piperazin-1-yl)benzoic acid

Suppliers and Price of 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]benzoic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]benzoicAcid
100mg
$ 500.00

TRC
4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]benzoicAcid
250mg
$ 1110.00

Matrix Scientific
4-(4-((4'-Chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid 95+%
250mg
$ 1853.00

Crysdot
4-(4-((4'-Chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoicacid 95+%
1g
$ 255.00

Chemenu
4-(4-((4''-Chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1''-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoicacid 95%
1g
$ 542.00

American Custom Chemicals Corporation
4-(4-((4'-CHLORO-4,4-DIMETHYL-3,4,5,6-TETRAHYDRO-[1,1'-BIPHENYL]-2-YL)METHYL)PIPERAZIN-1-YL)BENZOIC ACID 95.00%
5MG
$ 497.33

Alichem
4-(4-((4'-Chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoicacid
1g
$ 853.87

AK Scientific
4-(4-((4'-Chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoicacid
250mg
$ 363.00

Total 30 raw suppliers

Chemical Property of 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]benzoic Acid

Chemical Property:

Melting Point:191-193°C
PSA：43.78000
LogP:5.82700
Storage Temp.:Refrigerator
Solubility.:DMSO, Methanol

Purity/Quality:

99%, ^*data from raw suppliers

4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]benzoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Intermediate in the production of cell death regulators and apoptosis promoters.

Technology Process of 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]benzoic Acid

There total 8 articles about 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]benzoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1065604-70-7
ethyl 4-(4-((4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl) benzoate

: 1044598-91-5
4-(4-((4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; methanol; water; at 80 ℃; for 10h;

Reference yield: 88.4%

: 1044598-93-7
tert-butyl 4-(4-{[2-(4-chlorophenyl)-2-hydroxy-5,5-dimethylcyclohexyl]methyl}piperazin-1-yl)benzoate

: 1044598-91-5
4-(4-((4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; water; for 6h; Reflux;
DOI:10.1039/c0cc02969f

Reference yield:

: 80518-57-6
ethyl 4-(piperazin-1-yl)benzoate

: 1044598-91-5
4-(4-((4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / dimethyl sulfoxide / 2 h / 100 °C

2: sodium hydroxide / tetrahydrofuran; water; methanol / 10 h / 80 °C

With potassium carbonate; sodium hydroxide; In tetrahydrofuran; methanol; water; dimethyl sulfoxide;