4'-Phosphopantetheine

Base Information

• Chemical Name: 4'-Phosphopantetheine
• CAS No.: 1019842-99-9
• Molecular Formula: C11H23N2O7PS
• Molecular Weight: 584.615
• Mol file: 1019842-99-9.mol

Synonyms:PPT;4'-PHOSPHOPANTETHEINE;2,8-bis(diphenylphosphoryl)dibenzo[b,d]thiophene;PPT , 2,8-bis(diphenylphosphoryl)dibenzo[b,d]thiophene

Chemical Property of 4'-Phosphopantetheine

Chemical Property:

• Boiling Point: 830.1±60.0 °C(Predicted)
• PSA: 82.00000
• Density: 1.34±0.1 g/cm3(Predicted)
• LogP: 7.33330

Purity/Quality:

97% ^*data from raw suppliers

PPT sublimed ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: PPT is an ambipolar?phosphorescent host materials with an electron-rich dibenzothiophene core and two electron-deficient?diphenyl-phosphoryl side arms.? For this reason,?PPT is a good electron-transport material with higher electron mobility rate, offering better electron injection.

Technology Process of 4'-Phosphopantetheine

There total 3 articles about 4'-Phosphopantetheine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2,8-dibromodibenzothiophene (31574-87-5) + chloro-diphenylphosphine (1079-66-9,74391-44-9) → 2,8-bis(diphenylphosphoryl)dibenzo[b,d] thiophene (1019842-99-9)

Guidance literature:

2,8-dibromodibenzothiophene; With n-butyllithium; In tetrahydrofuran; at -80 ℃; for 2h; Inert atmosphere;

chloro-diphenylphosphine; In tetrahydrofuran; at 20 ℃; for 12h; Inert atmosphere;

With dihydrogen peroxide; In dichloromethane; water; at 20 ℃; for 2h; Inert atmosphere;

Reference yield: 46.0%

C36H26P2S (1258319-81-1) → 2,8-bis(diphenylphosphoryl)dibenzo[b,d] thiophene (1019842-99-9)

Guidance literature:

With dihydrogen peroxide; In dichloromethane; at 20 ℃;

DOI:10.1039/c1jm12421h

Reference yield:

dibenzothiophene (132-65-0) → 2,8-bis(diphenylphosphoryl)dibenzo[b,d] thiophene (1019842-99-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: bromine / chloroform / 24 h / 20 °C / Inert atmosphere

2.1: n-butyllithium / tetrahydrofuran / 2 h / -78 °C / Inert atmosphere

2.2: 8 h / -78 - 0 °C

With n-butyllithium; bromine; In tetrahydrofuran; chloroform;

DOI:10.1021/acs.chemmater.5b02012

upstream raw materials:

C₃₆H₂₆P₂S

2,8-dibromodibenzothiophene

chloro-diphenylphosphine

dibenzothiophene